Deep-Seated Giant Lipoma on the Hand Inducing Carpal Tunnel Syndrome

Kim, Dae Geun; Hwang, Sung-Il

doi:10.15746/sms.20.005

Cited by 3 publications

(9 citation statements)

References 11 publications

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“…Os primeiros sintomas, assim como o tamanho do tumor e preocupações estéticas, são indicações para a cirurgia. 3,9 Vários casos de compressão do nervo mediano foram relatados na literatura, simulando a síndrome do túnel do carpo, 1,2,5,6 mas há pouquíssimas descrições de comprometimento do movimento do polegar por compressão do ramo motor do nervo mediano. 9 Nosso caso apresentava disfunção da musculatura tênar, comprovada por estudos de EMG, além de formigamento nos dedos por neuropatia do nervo mediano, que foi provocada pela compressão do lipoma.…”

Section: Discussionunclassified

“…3,9 Vários casos de compressão do nervo mediano foram relatados na literatura, simulando a síndrome do túnel do carpo, 1,2,5,6 mas há pouquíssimas descrições de comprometimento do movimento do polegar por compressão do ramo motor do nervo mediano. 9 Nosso caso apresentava disfunção da musculatura tênar, comprovada por estudos de EMG, além de formigamento nos dedos por neuropatia do nervo mediano, que foi provocada pela compressão do lipoma. A maioria dos lipomas é superficial e pode comprimir as estruturas palmares acima, enquanto os lipomas profundos podem se fundir a nervos ou tendões de várias maneiras.…”

Section: Discussionunclassified

“…Essas estruturas podem repousar acima do tumor 10 ou mesmo atravessá-lo. 9 Nosso caso representa uma imagem muito rara do ramo motor recorrente do nervo mediano, que passava sobre o tumor, entre seus dois lobos, e era vulnerável durante a excisão.…”

Section: Discussionunclassified

“…The former symptoms along with tumor size and cosmetic concerns, are indications for surgery. 3,9 Several cases of median nerve compression have been reported in the literature, mimicking a carpal tunnel syndrome, 1,2,5,6 but very few cases are reported having a compromised thumb motion due to compression of the median nerve's motor branch. 9 Our case involved dysfunction of the thenar muscles, confirmed by EMG studies, in addition to fingers' tingling due to median nerve neuropathy, which was caused by compression of the lipoma.…”

Section: Discussionmentioning

confidence: 99%

“…3,9 Several cases of median nerve compression have been reported in the literature, mimicking a carpal tunnel syndrome, 1,2,5,6 but very few cases are reported having a compromised thumb motion due to compression of the median nerve's motor branch. 9 Our case involved dysfunction of the thenar muscles, confirmed by EMG studies, in addition to fingers' tingling due to median nerve neuropathy, which was caused by compression of the lipoma. Most lipomas are superficial, and they might compress palmar structures from above, whereas deep lipomas can blend with nerves or tendons in various ways.…”

Section: Discussionmentioning

confidence: 99%

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Neuropatia sensorial e motora do nervo mediano por um lipoma gigante na mão: Relato de caso

Stavrakakis

Georgopoulou

Magarakis

et al. 2021

Rev Bras Ortop (Sao Paulo)

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ResumoOs lipomas são os tumores de partes moles mais comuns no corpo humano, mas sua localização na mão é rara. Os lipomas de mão que causam sintomas por compressão do nervo são ainda mais raros. Apresentamos um caso de neuropatia do nervo mediano decorrente de um lipoma palmar gigante, localizado nas regiões tenar e hipotenar da mão. A paciente apresentava sintomas típicos de síndrome do túnel do carpo, além de comprometimento dos movimentos do polegar. Durante a cirurgia, o ramo motor recorrente do nervo mediano repousava sobre o lipoma sob grande tensão. Esta localização particular do ramo motor do nervo mediano em relação ao lipoma torna este caso único. O tumor foi extirpado, protegendo as estruturas neurovasculares e, poucas semanas depois, a paciente havia recuperado totalmente os movimentos do polegar e força de preensão, além de apresentar resolução da disestesia.

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Section: Discussionunclassified

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Neuropatia sensorial e motora do nervo mediano por um lipoma gigante na mão: Relato de caso

Stavrakakis

Georgopoulou

Magarakis

et al. 2021

Rev Bras Ortop (Sao Paulo)

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Conventional Cytogenetic and Molecular Analysis in Acute Myeloid Leukemia (AML) and Their Association with Overall Survival

Shakeri

Javan

Ayatollahi

et al. 2021

Acta Medica Bulgarica

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Background: Conventional cytogenetic is one of the most important diagnostic tools for predicting the overall survival of the patients. Molecular genetics in acute myeloid leukemia (AML) has provided insights into the molecular mechanism of leukemogenesis. In this study we aimed to investigate the impact of cytogenetic and molecular methods on the survival of patients with de novo established AML in order to achieve a useful marker or test in the process of predicting the disease course. Material and methods: Eighty newly diagnosed AML patients who were treatment naive entered the study. Cytogenetic and molecular studies such as, the conventional karyotyping, sequencing and reverse transcriptase real time quantitative PCR (RT-qPCR) were included. Overall survival was calculated by Kaplan-Maier technique and the data were analyzed by SPSS.V.19. Results: Among 80 patients, 36 (45%) were female and 44 (55%) were male patients. Patients’ median age was 29 years, ranging from 1 to 76 years. The mean overall survival was 19 months (95% CI: 1523 months). The 1-year AML survival rate was 61%. There were significant differences in overall survival between the NPM1-mutated groups compared to the patients without any mutations (19% versus 61%) (p < 0.032). Conclusion: This study makes a significant contribution in assessing the prognostic value of cytogenetic and molecular markers. This study showed the heterogeneity of de novo AML that involved various factors and prevalence of distinct cytogenetic subgroups. Our data in comparison with other population-based studies, confirmed a differential distribution of cytogenetic and molecular classification indicating geographic heterogeneity.

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Giant Lipoma of the Hand

Georgiev,

Telang,

Firoozi

et al. 2022

Acta Medica Bulgarica

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Lipomas have been called “innocent tumors” due to their slow growth without infiltrating neighbouring structures, usually with a rounded or ovoid shape, rarely over 2 cm in size. In the area of the upper limb, lipomas over 5 cm are defined as “giant lipomas”. In this report, we present a rare case of a “giant lipoma” in the hand in a 60-year-old man. He complained of painless swelling, which appeared eight years before and gradually increased in size until the last year, when a significant enlargement appeared; thus, the soft tissue mass led to the inability to perform daily tasks, and the patient sought medical care. Computed tomography suggested the diagnosis of lipoma. Thereafter, successful surgical excision was performed, and no recurrences were observed two years after the operation. The clinical signs, imaging, and treatment methods of this case are briefly presented.

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Deep-Seated Giant Lipoma on the Hand Inducing Carpal Tunnel Syndrome

Cited by 3 publications

References 11 publications

Neuropatia sensorial e motora do nervo mediano por um lipoma gigante na mão: Relato de caso

Neuropatia sensorial e motora do nervo mediano por um lipoma gigante na mão: Relato de caso

Conventional Cytogenetic and Molecular Analysis in Acute Myeloid Leukemia (AML) and Their Association with Overall Survival

Giant Lipoma of the Hand

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