Deep tissue photoacoustic imaging of nickel(II) dithiolene-containing polymeric nanoparticles in the second near-infrared window

Park, Byullee; Lee, Kyung Min; Park, Suhyeon; Yun, Misun; Choi, Hang Seok; Lee, Chang-Ho; Kim, Hyungwoo; Kim, Chulhong

doi:10.7150/thno.39403

Cited by 78 publications

(68 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Metal sulfides, such as copper sulfide (CuS), tungsten sulfide (WS 2 ), and molybdenum sulfide (MoS 2 ), have been widely used for PAI and photothermal therapy (PTT) as novel optical molecular imaging reagents [35][36][37][38][39]. Taking Cu 2-x S as an example, recent research revealed that the LSPR effect could be regulated by altering the composition ratio of Cu/S to realize the application of Cu 2-x S in NIR-II PAI.…”

Section: Metal Chalcogenides-based Nanomaterialsmentioning

confidence: 99%

Development of Second Near-Infrared Photoacoustic Imaging Agents

Zhang¹,

Ning²,

Zeng³

et al. 2021

Trends in Chemistry

View full text Add to dashboard Cite

Section: Metal Chalcogenides-based Nanomaterialsmentioning

confidence: 99%

Development of Second Near-Infrared Photoacoustic Imaging Agents

Zhang¹,

Ning²,

Zeng³

et al. 2021

Trends in Chemistry

View full text Add to dashboard Cite

“…For potential clinical applications, clinical US machines have been used for PACT. As the receiving signals of both PA and US are acoustic waves, the signal acquisition and image reconstruction procedures of the two imaging techniques are identical, and they can thus share a single imaging platform [ 27 , 50 , 51 , 52 ]. Combined PA and US images, providing complementary structural and functional information regarding biological tissues, have been investigated in clinical applications such as melanoma detection, cancer classification, and vascular disease assessment [ 53 , 54 , 55 , 56 ].…”

Section: Photoacoustic Imaging Systemmentioning

confidence: 99%

Recent Trends in Photoacoustic Imaging Techniques for 2D Nanomaterial-Based Phototherapy

et al. 2021

Self Cite

View full text Add to dashboard Cite

A variety of 2D materials have been developed for therapeutic biomedical studies. Because of their excellent physicochemical properties, 2D materials can be used as carriers for delivering therapeutic agents into a lesion, leading to phototherapy. Various optical imaging techniques have been used for the monitoring of the treatment process. Among these, photoacoustic imaging has unique advantages including relatively deep imaging depth and large field of view with high spatial resolution. In this review article, we summarize the types of photoacoustic imaging systems used for phototherapy monitoring, then we explore contrast-enhanced photoacoustic images using 2D materials. Finally, photoacoustic image-guided phototherapies are discussed. We conclude that 2D material-based phototherapy can be efficiently monitored by photoacoustic imaging techniques.

show abstract

“…With PAI, anatomical structures are easily visualized, and functional information such as blood oxygenation, oxygen saturation, blood flow, and metabolism can be obtained [ 18 , 19 ]. Owing to its flexible imaging system configuration, which allows a specific resolution and penetration depth, PAI is used in various biomedical applications [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 ]. PA computed tomography (PACT) focuses on reconstructing an image from one-dimensional radial information defining the relationship between the PA source and the detector position.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Quantitative Vasculature Segmentation and Assessment for Photodynamic Therapy Process Monitoring Using Photoacoustic Microscopy

Thao

Yoo

Park

et al. 2021

Sensors

Self Cite

View full text Add to dashboard Cite

Vascular damage is one of the therapeutic mechanisms of photodynamic therapy (PDT). In particular, short-term PDT treatments can effectively destroy malignant lesions while minimizing damage to nonmalignant tissue. In this study, we investigate the feasibility of label-free quantitative photoacoustic microscopy (PAM) for monitoring the vasculature changes under the effect of PDT in mouse ear melanoma tumors. In particular, quantitative vasculature evaluation was conducted based on Hessian filter segmentation. Three-dimensional morphological PAM and depth-resolved images before and after PDT treatment were acquired. In addition, five quantitative vasculature parameters, including the PA signal, vessel diameter, vessel density, perfused vessel density, and vessel complexity, were analyzed to evaluate the influence of PDT on four different areas: Two melanoma tumors, and control and normal vessel areas. The quantitative and qualitative results successfully demonstrated the potential of the proposed PAM-based quantitative approach to evaluate the effectiveness of the PDT method.

show abstract

Deep tissue photoacoustic imaging of nickel(II) dithiolene-containing polymeric nanoparticles in the second near-infrared window

Cited by 78 publications

References 63 publications

Development of Second Near-Infrared Photoacoustic Imaging Agents

Development of Second Near-Infrared Photoacoustic Imaging Agents

Recent Trends in Photoacoustic Imaging Techniques for 2D Nanomaterial-Based Phototherapy

In Vivo Quantitative Vasculature Segmentation and Assessment for Photodynamic Therapy Process Monitoring Using Photoacoustic Microscopy

Contact Info

Product

Resources

About