Deep vein thrombosis associated with protein C and protein S deficiency: An unusual cause of acute abdomen

Doğanay, Selim; Sönmezgöz, Fitnet; Şen, Yaşar; Kocakoç, Ercan

doi:10.1002/jcu.20771

Cited by 1 publication

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In patients with venous thromboembolism, the prevalence of deficiency of protein-C and protein-S was 2-5%. [4][5][6][7] Here, we report a case of a women who is in her twenties, already had a history of deep vein thrombosis, and yet again diagnosed with chronic abdominal venous thrombosis including portal vein, bilateral iliofemoral vein and inferior venacava.…”

Section: Discussionmentioning

confidence: 94%

Recurrent abdominal and lower limb venous thrombosis due to inherent protein-C and protein-S deficiency

Polavarapu¹,

Narayanasamy²,

Subramanian³

2019

Int J Res Med Sci

View full text Add to dashboard Cite

Protein-C and protein-S deficiency is associated with a hypercoagulable state which usually presents with recurrent venous thrombosis as a common complication. But extensive thrombosis involving all the major abdominal and lower limb veins is quite rare. Here, we report a case of a 27-year-old woman presented with engorged veins all over abdomen and chest since 20 days. Clinical examination revealed signs suggestive of portal venous hypertension with moderate splenomegaly. Protein-C and protein-S levels were found to be low. Portal venous doppler ultrasound and CT-venogram revealed chronic thrombosis of portal vein, inferior vena cava, bilateral iliac and femoral veins with extensive collaterals formation and partial thrombosis in collaterals as well. The patient was successfully managed with anti-coagulating agent (acenocoumarol) and has been maintained on regular follow-up to avoid reoccurrence of thrombosis.

show abstract

Section: Discussionmentioning

confidence: 94%