Deep Venous Thrombosis among hypertensive patients in King Abdulaziz University (KAU) Hospital, Jeddah, Kingdom of Saudi Arabia

Alanazi, Omar; El-Fetoh, Nagah Mohamed Abo; Mohammed, Nesreen; Alanizy, Tariq Mozil Aquab; Alanazi, Yasir Wadi; Alanazi, Munif Saleh; Alrwaili, Abdurhman Aiash; Alruwaili, Amjad Hamoud; Alanazi, Abdullah Hussain; Alanazi, Ahmed Z.

doi:10.19082/5472

Cited by 5 publications

(7 citation statements)

References 24 publications

(31 reference statements)

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“…In terms of hypertension, its association with the development of DVT is a controversial issue. Some previous studies suggested that hypertension could increase the risk of DVT6, but some other studies concluded that there was no statistically significant association between it and DVT 15. However, in the current study, we confirmed that hypertension was an independent risk factor for DVT in patients with gynecological malignant tumor.…”

Section: Discussionsupporting

confidence: 70%

Analysis of risk factors for deep venous thrombosis in patients with gynecological malignant tumor: A clinical study

Xue

Yuan

2019

Pak J Med Sci

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Objectives: To determine the clinical characteristics and risk factors of Deep Venous Thrombosis (DVT) in patients with gynecological malignant tumor, facilitating gynecologists better prevent the fatal complication. Methods: The patients with gynecological malignant tumor treated in department of gynecology of our hospital between May 2013 and May 2018 were reviewed retrospectively. The clinical data of patients including gender, age, tumor staging, adenocarcinoma, surgery, operation time, hypertension, hyperlipemia, diabetes, coronary heart disease, radiotherapy, chemotherapy, hospital stay, and postoperative rehabilitation exercise were collected to analyze the clinical characteristics of patients and determine the risk factors of DVT. Results: In the current study, 67 patients were included in DVT group, and 554 patients were included in Non-DVT group. There were significant differences in age, hypertension, hyperlipemia, operation time, adenocarcinoma, tumor staging, radiotherapy and postoperative rehabilitation exercises between DVT and non-DVT groups (p<0.05). However, there was no significant differences in gender, coronary heart disease, diabetes, surgical treatment and hospital stay (p>0.05). In multivariate analysis, the factors including age, hypertension, adenocarcinoma, radiotherapy, and hyperlipemia were independent risk factors, while rehabilitation exercise was protective factor for DVT. Conclusion: In cases of gynecological malignant tumor, DVT screening should be given due importance, especially for those patients with old age, hypertension, hyperlipemia, adenocarcinoma, or history of radiotherapy. Rehabilitation exercise should be encouraged in these patients. How to cite this:Li Q, Xue Y, Peng Y, Li L. Analysis of risk factors for deep venous thrombosis in patients with gynecological malignant tumor: A clinical study. Pak J Med Sci. 2019;35(1):---------. doi: https://doi.org/10.12669/pjms.35.1.365 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionsupporting

confidence: 70%

Analysis of risk factors for deep venous thrombosis in patients with gynecological malignant tumor: A clinical study

Xue

Yuan

2019

Pak J Med Sci

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“…Second, our cases were mostly obese or overweight (BMI ranged from 20.1 to 39.8 with a mean of 28.16 ± 4.90 kg/m2), which has been linked to an increased risk of PE in previous studies [13] . Thirdly, the presence of a high incidence of smoking (40%) in our cases is a risk factor for the development of thromboembolic events [14] , in addition to the controversial roles of high incidences of hypertension and diabetes (72% and 32%, respectively) [15] . Lastly, the possible late presentations and lack of resources for diagnosis and management may have a role in this high incidence of embolic complications in our patients.…”

Section: Discussionmentioning

confidence: 67%

Radiological Assessment of the Vascular Complications of Covid-19 in Correlation With D-Dimer Level

Abdel Aziz,

Yosry,

Elshimy

2023

Ain Shams Medical Journal

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Background:The COVID-19 pandemic causes primarily respiratory disease as well as non-respiratory complications such as thromboembolic complications with D-dimer elevation, which lead to multisystem organ dysfunction and respiratory failure. Aim of the work: To determine the value of radiological assessment of vascular complications in COVID-19 infections and its relation to D-dimer levels as important tools for early diagnosis and proper management of these patients.Patients & Methods: The study included 100 patients diagnosed as COVID-19 positive with embolic manifestations depending on their symptoms, signs, and laboratory assessment, which included D-dimer levels. They underwent radiological assessment of their vascular complications, including CT, MRI, and CT angiography.Results: Among 100 COVID-positive patients with thromboembolic symptoms, 55 had evidence of pulmonary embolism, 13 had strokes, 4 had mesenteric arterial occlusion and 28 patients had no radiological evidence of vascular manifestations. D-dimer levels were increased (0.50 mcg/mL or greater) in 70 percent of positive COVID patients, including 89% of those with pulmonary embolism, 84% of those with stroke, 75% of mesenteric thrombosis cases, and in 7 patients (25% of those with symptoms suggestive of vascular thrombosis without radiological imaging of thromboembolic manifestations), with a sensitivity of 88.6%, specificity of 75%, positive predictive value of 90.9%, and negative predictive value of 70%. Conclusion:This study confirmed that D-dimer elevation in COVID-positive patients is highly suggestive of thromboembolic complications, especially pulmonary, cranial, and abdominal embolisms, and that confirmation by proper radiological evaluation is mandatory for the diagnosis of these findings and proper management of their complications.

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“…The higher incidence of UEDVTs in patients with PICC lines, as opposed to central venous lines, may be explained by the fact that PICC lines traverse a longer route through the venous system and have a higher catheter:vein-diameter ratio than central lines, all increasing hypercoagulability. 11 What was interesting to see was that while PICC lines and CVCs posed significantly increased risk of developing UEDVT, patients with implanted pacemakers or cardiac implantable electronic devices did not have an increased risk of developing UEDVT ( p =0.181). This could be explained by the varying approaches to implanting such devices (either endovascularly or surgically) and the fact that a shorter vein is disturbed with endovascular placement compared to central lines or PICC lines, decreasing the risk of thrombus development.…”

Section: Discussionmentioning

confidence: 99%

“…This could be explained by the varying approaches to implanting such devices (either endovascularly or surgically) and the fact that a shorter vein is disturbed with endovascular placement compared to central lines or PICC lines, decreasing the risk of thrombus development. 11 …”

Section: Discussionmentioning

confidence: 99%

Predictable Risk Factors of Upper-Extremity Deep Venous Thrombosis in a Level I Trauma Center

Tohme

Vancheswaran

Mobbs

et al. 2021

IJGM

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Background Venous thromboembolism is a common cause of morbidity and mortality in hospital patients, especially that of the lower extremities. Risk factors and diagnostic elements of upper-extremity deep-vein thrombosis (UEDVT) are poorly understood compared to those of the lower extremities. The primary objectives of this study were to identify predictive risk factors of secondary UEDVT. Methods This retrospective study included all nonpregnant patients aged >18 years who had undergone upper-extremity duplex scans to check for the presence of secondary UEDVT at Richmond University Medical Center from January 2014 to March 2020. Patients were stratified by presence or absence of UEDVT. Collected data points included patient demographics, comorbidities, central-line use, platelet count at time of scan, length of stay, and overall mortality. IBM 27.0 was used for all statistical analysis, with p<0.05 considered significant. Results A total of 1,009 upper extremity venous duplex studies were included. There were no significant differences in age, sex, race, or mean platelet levels between patients diagnosed with DVT and those without ( p <0.05). After multinomial regression analysis, central venous catheter (CVC; 26.8% versus 78.5%, aOR 1.770, 95% CI 1.150–2.725; p <0.002), peripherally inserted central catheter (PICC) line (17.5% versus 82.5%, aOR3.254, 95% CI 1.997–5.304; p <0.001), hypertension (67.8% versus 28.8%, aOR 1.641, 95% CI 1.136–2.369; p <0.001), chronic kidney disease (CKD; 34.5% versus 65.5%, aOR 1.743, 95% CI 1.201–2.531; p <0.001), and malignancy (27.1% versus 74.6%, aOR 1.475, 95% CI 0.994–2.190; p <0.053) were found to be independent predictors of UEDVT. Conclusion Use of CVC or PICC line, preexisting diagnosis of hypertension, malignancy, and CKD were independent risk factors of UEDVT, while there was no significant correlation between increased platelet levels and UEDVT.

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Deep Venous Thrombosis among hypertensive patients in King Abdulaziz University (KAU) Hospital, Jeddah, Kingdom of Saudi Arabia

Cited by 5 publications

References 24 publications

Analysis of risk factors for deep venous thrombosis in patients with gynecological malignant tumor: A clinical study

Analysis of risk factors for deep venous thrombosis in patients with gynecological malignant tumor: A clinical study

Radiological Assessment of the Vascular Complications of Covid-19 in Correlation With D-Dimer Level

Predictable Risk Factors of Upper-Extremity Deep Venous Thrombosis in a Level I Trauma Center

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