Deep venous thrombosis and pulmonary embolism after COVID-19 mRNA vaccination

Atoui, Ali; Jarrah, Kawthar; Mahmasani, Layal Al; Bou‐Fakhredin, Rayan; Taher, Ali T.

doi:10.1007/s00277-021-04743-1

Cited by 14 publications

(19 citation statements)

References 12 publications

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“…Immune thrombocytopenic purpura (ITP) has been associated with several vaccinations, including measles, mumps, rubella (MMR), hepatitis A, varicella, diphtheria, tetanus, pertussis (DPT), oral polio and influenza ( Perricone et al, 2014 ). While there is broad awareness that the adenovirus DNA-based vaccines can cause vaccine-induced immune thrombotic thrombocytopenia (VITT) ( Kelton et al, 2021 ), the mRNA vaccines are not without risk to VITT, as case studies have been published documenting such occurrences, including life threatening and fatal cerebral venous sinus thrombosis ( Lee et al, 2021 ; Akiyama et al, 2021 ; Atoui et al, 2022 ; Zakaria et al, 2021 ). The mechanism is believed to involve VITT antibodies binding to platelet factor 4 (PF4) and forming immune complexes that induce platelet activation.…”

Section: Immune Thrombocytopeniamentioning

confidence: 99%

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

Seneff¹,

Nigh

Kyriakopoulos³

et al. 2022

Food and Chemical Toxicology

131

119

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Section: Immune Thrombocytopeniamentioning

confidence: 99%

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

Seneff¹,

Nigh

Kyriakopoulos³

et al. 2022

Food and Chemical Toxicology

131

119

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“…We previously discussed a study revealing that there was no increase in the incidence of PE in people aged 75 years old and older 14 days after each BNT162b2 vaccination, but there exist some rare reports regarding PE [ 87 , 92 ]. A recent post-vaccination venous thromboembolism and PE report presents a 24-year-old boy, and the authors discuss his thrombophilia screening, which showed an FVL G169A heterozygous mutation and MTHFR A1298C homozygous mutation, trying to explain the event through the inherited thrombophilia [ 93 ]. The authors conclude that patients with a history of unprovoked DVT or PE who have not been tested for genetic risk should be offered testing before vaccination, as there is presently insufficient evidence to warrant their exemption from vaccination or the use of anticoagulant prophylaxis [ 93 ].…”

Section: Mrna Vaccination Against Covid-19 and Diagnosis Of Spontaneo...mentioning

confidence: 99%

Current Evidence in SARS-CoV-2 mRNA Vaccines and Post-Vaccination Adverse Reports: Knowns and Unknowns

Mouliou

Dardiotis

2022

Diagnostics

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The novel mRNA vaccinations against COVID-19 are gaining worldwide attention for their efficacy, as well as the diagnosis of some post-vaccination-reported adverse reactions. In this state-of-the-art review article, we present the current evidence regarding mainly the diagnosis of spontaneous allergic reactions, the skin occurrences, the vascular, blood, endocrine and heart events, the respiratory reports, the gastrointestinal, hepatic and kidney events, the reproductive and pregnancy issues and the muscle events, as well as the ear, eye, neurologic and psychiatric events following mRNA vaccination against COVID-19. We further present some evidence regarding the mRNA strategies and we discuss our expert opinion on the knowns and the unknowns towards the topic.

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“…In addition to the more common venous thromboses in the lower extremities, vaccine-related clotting occurs in atypical locations like cerebral sinuses and intestinal veins [246][247][248][249][250][251]. (Figure 1) Venous thrombosis, in turn, leads to a higher incidence of pulmonary embolism [252]. (Figure 2) Such events prompted the temporary withdrawal of the J & J vaccine in Europe and the US.…”

Section: Messengers Of Hope?mentioning

confidence: 99%

COVID-19 and the Unraveling of Experimental Medicine - Part II

Thorp¹,

Thorp²

2022

G Med Sci

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In the second part of our trilogy, we begin by examining social policies sponsored by the science community and enacted by policy-makers to curtail the dynamics of the COVID-19 pandemic. Containment /mitigation strategies such as lockdowns came at great social and economic costs and yet failed to meaningfully impact the spread and evolution of the SARS-CoV-2 virus. Evidence suggests the social fallout alone from such strategies exceeded the morbid sequelae of the pandemic itself. We then examine the logic driving the one and only strategy advanced by the science community, i.e., vaccination, to neutralize SARS-CoV-2 and induce herd immunity. Evidence overwhelmingly points in but one direction: the mRNA vaccines were an unqualified failure. They neither halted viral spread nor conferred herd immunity and, in their wake, spawned a laundry list of disabling side effects. We point to a 40-fold increase in adverse event reports compared to trivalent influenza vaccines in the years preceding the pandemic. Medical science must now confront the possibility of yet another mass casualty event which, in all likelihood, will surpass any of the pharmacologically-induced disasters of the 20th century.

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Deep venous thrombosis and pulmonary embolism after COVID-19 mRNA vaccination

Cited by 14 publications

References 12 publications

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

Current Evidence in SARS-CoV-2 mRNA Vaccines and Post-Vaccination Adverse Reports: Knowns and Unknowns

COVID-19 and the Unraveling of Experimental Medicine - Part II

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