Deep Venous Thrombosis and Pulmonary Embolism in Cardiac Surgical Patients

Khoury, Habib; Lyons, Robert W.; Sanaiha, Yas; Rudasill, Sarah; Shemin, Richard J.; Benharash, Peyman

doi:10.1016/j.athoracsur.2019.09.055

Cited by 27 publications

(18 citation statements)

References 37 publications

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“…There was no infectious endocarditis, which was clinically considered and consists of one of the complications of valve prolapse. 13 The closure of the atrial septal defect and CABG did not have any complications. It should be noted that coronary artery disease was of atherosclerotic origin and did not have any major myocardial consequences, with only mild left ventricular myocardiosclerosis.…”

Section: Commentsmentioning

confidence: 87%

Caso 1/2020 - Mulher de 55 Anos com Insuficiência Cardíaca após Internação por Diagnóstico Presumido de Infarto do Miocárdio e Insuficiência da Valva Mitral com Rotura de Corda Tendínea

Favarato¹,

Benvenuti²

2020

Arquivos Brasileiros De Cardiologia

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Section: Commentsmentioning

confidence: 87%

Caso 1/2020 - Mulher de 55 Anos com Insuficiência Cardíaca após Internação por Diagnóstico Presumido de Infarto do Miocárdio e Insuficiência da Valva Mitral com Rotura de Corda Tendínea

Favarato¹,

Benvenuti²

2020

Arquivos Brasileiros De Cardiologia

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“…It is established that increasing age, multiple comorbidities and male sex increases the probability of a pulmonary embolic event [33][34][35]. This may be related in part to increased activation of blood coagulation, fibrinolysis, and inflammation, possibly related to the increased inflammatory burden of both atherosclerotic and non-vascular disease.…”

Section: Discussionmentioning

confidence: 99%

The Use of End-Tidal CO2 as a Screening Tool in Patients with Pulmonary Embolism

2021

Eur J Respir Med

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Pulmonary Embolism (PE) is a global problem and a leading cause of cardiovascular death in the western world and a major public health problem [1,2]. The diagnosis of PE remains a challenge because of the high variability in clinical presentation complex interplay between different organs. Patients can present with chest pain, dyspnoea, haemoptysis, syncope and hypoxaemia [3,4]. Diagnosis of a PE is confirmed in <25% of patients that are clinically suspicious and the radiological investigations are essential [5,6]. Despite the low relative incidence of the disease, there is a significant rise in the number of patients undergoing unnecessary computed tomography pulmonary angiograms (CTPA) to exclude a PE. Moreover, the CTPA is the most robust predictive evidence base for adverse clinical outcomes in patients with acute PE [7,8].In most centres, patients with a high clinical suspicion of PE undergo serum D-dimer assessment as a screening test and it has a value in ruling out PE [9,10]. Treatment is initiated on those with a positive D-dimer and continuation of treatment is determined by the outcome of the CTPA scan [9]. Measurement of serum D-dimer requires venipuncture and results are not immediate [9]. CTPA scans are associated with high cost and exposure to radiation and nephrotoxic contrasts, a worrying concept

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“…Cardiac surgery increases the likelihood of post-operative thromboembolic complications in both children and adults ( 4 , 26 – 28 ). The reported increased risk of thrombosis following Fontan surgery is likely multi-factorial, owing to the insertion of central venous lines, the use of cardiopulmonary bypass and the variable surgical manipulation of tissue ( 29 – 31 ).…”

Section: Te Post-fontan Surgerymentioning

confidence: 99%

Increased Risk for Thromboembolism After Fontan Surgery: Considerations for Thromboprophylaxis

et al. 2022

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The Fontan circulation introduces an increased risk of thromboembolism which is associated with substantial mortality and morbidity. Adverse outcomes of thromboembolic complications post-Fontan surgery vary in both nature and severity, ranging from local tissue infarction and pulmonary embolism to Fontan failure and ischemic stroke. Furthermore, recent studies have identified that subclinical stroke is common yet underdiagnosed in Fontan patients. Fontan patients are commonly treated with antiplatelet agents and/or anticoagulants as primary thromboprophylaxis. Optimal thromboprophylaxis management in the Fontan population is still unclear, and clinical consensus remains elusive despite the growing literature on the subject. This perspective will describe the nature of thromboembolism post-Fontan surgery and provide evidence for the use of both current and emerging thromboprophylaxis options for children and adults living with Fontan circulation.

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Deep Venous Thrombosis and Pulmonary Embolism in Cardiac Surgical Patients

Cited by 27 publications

References 37 publications

Caso 1/2020 - Mulher de 55 Anos com Insuficiência Cardíaca após Internação por Diagnóstico Presumido de Infarto do Miocárdio e Insuficiência da Valva Mitral com Rotura de Corda Tendínea

Caso 1/2020 - Mulher de 55 Anos com Insuficiência Cardíaca após Internação por Diagnóstico Presumido de Infarto do Miocárdio e Insuficiência da Valva Mitral com Rotura de Corda Tendínea

The Use of End-Tidal CO2 as a Screening Tool in Patients with Pulmonary Embolism

Increased Risk for Thromboembolism After Fontan Surgery: Considerations for Thromboprophylaxis

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