Deep venous thrombosis in the antenatal period in a large cohort of pregnancies from western India

Abstract

Background: Deep venous thrombosis (DVT) is an important complication in the peripartal and postpartal period.

Thrombophilia among Chinese Women with Venous Thromboembolism during Pregnancy

“…The small number of controls also does not allow an estimation of relative risks of different thrombophilia in the occurrence of VTE during pregnancy, which will require a large population screening. Another limitation is that some other known – but less common – thrombophilia, such as factor XIII V34L, plasminogen activator inhibitor-1, endothelial PC receptor polymorphisms, were not included in the present study [36,40,41]. Recent studies also discovered new gene variants CYP4V2, SERPINC1, GP6 HIVEP1 locus and von Willebrand factors, which will be worth pursuing for future study [42,43,44,45].…”

Changes in coagulation and hemodynamics during pregnancy: a prospective longitudinal study of 58 cases

“…The pathogenesis of many diseases during pregnancy is believed to be related with thrombosis or prothrombosis, for example fetal growth restriction, spontaneous abortions, and preeclampsia [2][3][4]. And venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), remains a leading cause of maternal death, causing 1.2-4.7 deaths per 100,000 pregnancies [5,6]. Recently, studies have suggested that hypercoagulability occurs in normal and pathologic pregnancies, with differences between them.…”

Underlying prothrombotic states in pregnancy associated cerebral venous thrombosis

“…In a small series Cakmak et al, [13] found prothrombotic risk factors positive in 75% of CVT patients with CVT and in this study 38% of patients had multiple factors. Vora et al, [14] studied antenatal women with deep venous thrombosis and found 68% having two or more thrombophilic risk factors. This study showed association between some of the hereditary and acquired prothrombotic states and pregnancy associated deep vein thrombosis (DVT).…”