The search for structural and microstructural defects using simple human vision is associated with significant errors in determining voids, large pores, and violations of the integrity and compactness of particle packing in the micro- and macrostructure of concrete. Computer vision methods, in particular convolutional neural networks, have proven to be reliable tools for the automatic detection of defects during visual inspection of building structures. The study’s objective is to create and compare computer vision algorithms that use convolutional neural networks to identify and analyze damaged sections in concrete samples from different structures. Networks of the following architectures were selected for operation: U-Net, LinkNet, and PSPNet. The analyzed images are photos of concrete samples obtained by laboratory tests to assess the quality in terms of the defection of the integrity and compactness of the structure. During the implementation process, changes in quality metrics such as macro-averaged precision, recall, and F1-score, as well as IoU (Jaccard coefficient) and accuracy, were monitored. The best metrics were demonstrated by the U-Net model, supplemented by the cellular automaton algorithm: precision = 0.91, recall = 0.90, F1 = 0.91, IoU = 0.84, and accuracy = 0.90. The developed segmentation algorithms are universal and show a high quality in highlighting areas of interest under any shooting conditions and different volumes of defective zones, regardless of their localization. The automatization of the process of calculating the damage area and a recommendation in the “critical/uncritical” format can be used to assess the condition of concrete of various types of structures, adjust the formulation, and change the technological parameters of production.