Deferoxamine therapy of aluminum toxicity in dialysis patients

Charhon, S

doi:10.1007/978-94-009-1868-9_24

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1992

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“…In man the chelating drug deferoxamine is used as an antidote (21), but its use is controversial (14). The present dog recovered without further therapy.…”

Section: Discussionmentioning

confidence: 85%

Aluminium intoxication in a dog

Toor¹,

Voet

Ellen³

et al. 1990

Veterinary Quarterly

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SUMMARY.A two-year-old male Barsoi dog was presented after a two-week period of muscle twitching and convulsions during exercise, which worsened to a state of tetraparesis and coma.Removal of a gastric foreign body, containing aluminium, resolved the presenting signs.Parallel with this clinical recovery the elevated serum levels of aluminium decreased to values of two normal control dogs, suggesting that the neurological signs were due to A l intoxication.

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“…In man the chelating drug deferoxamine is used as an antidote (21), but its use is controversial (14). The present dog recovered without further therapy.…”

Section: Discussionmentioning

confidence: 85%

Aluminium intoxication in a dog

Toor¹,

Voet

Ellen³

et al. 1990

Veterinary Quarterly

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Resorption und Toxizität von Aluminium bei Niereninsuffizienz

Ittel

1992

Aktuelle Aspekte Der Osteologie

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Evidence of aluminium accumulation in aluminium welders.

Elinder

Ahrengart

Lidums

et al. 1991

Occupational and Environmental Medicine

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Aluminium is an abundant metal comprising about 8% of the earth's crust. Despite this, the concentration of aluminium in water, foodstuffs, and biological media is usually low.' For many years aluminium was considered innocuous and virtually not absorbed from the gastrointestinal tract.As a consequence of improved analytical facilities, it has been possible during the past decades to obtain accurate data on the concentration of aluminium in human media such as blood and urine. In 1976 Alfrey et al' showed that aluminium accumulates in patients

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Deferoxamine therapy of aluminum toxicity in dialysis patients

Cited by 3 publications

References 58 publications

Aluminium intoxication in a dog

Aluminium intoxication in a dog

Resorption und Toxizität von Aluminium bei Niereninsuffizienz

Evidence of aluminium accumulation in aluminium welders.

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