Deficiency of theory of mind in patients with remitted mood disorder

Inoue, Yumiko; Tonooka, Yuji; Yamada, Kazuo; Kanba, Shigenobu

doi:10.1016/j.jad.2004.04.004

Cited by 187 publications

(119 citation statements)

References 33 publications

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“…The current finding is consistent with previous studies of impairments in PT in patients with MDD (35)(36)(37). One explanation for this finding is that depressed individuals have difficulties letting go of an egocentric attitude in order to affirm the perspective of another person (38,39).…”

Section: Discussionsupporting

confidence: 92%

Relationship between empathic responding and its clinical characteristics in patients with major depressive disorder

Ekinci¹,

Ekinci²

2016

Dusunen Adam

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Relationship between empathic responding and its clinical characteristics in patients with major depressive disorder Objective: To our knowledge, there is no study specifically examining the relation between empathic responding and clinical features in patients with major depressive disorder (MDD). Our aim was to examine cognitive and affective empathic responding in patients with MDD and to explore the possible relations between clinical features and empathy. Method:The sociodemographic and clinical properties of 83 patients with major depression were recorded. The Beck Depression Inventory (BDI) was used to assess severity of depression, whereas the Beck Anxiety Inventory (BAI) was used to assess anxiety. Hopelessness level was measured by Beck Hopelessness Scale (BHS). Patients' empathic ability was evaluated by using the Interpersonel Reactivity Index (IRI), and results were compared with 85 healthy controls. We used Pearson correlation and general linear model analysis to evaluate the manner in which the variables contributed to the IRI scores.Results: Perspective Taking (IRI-PT), Empathic Concern (IRI-EC), and Fantasy (IRI-FS) subscores were all substantially lower in subjects with depression than in healthy controls, while the Personal Distress (IRI-PD) subscore was higher than in healthy subjects. There were significant effects of gender on the scores of IRI-EC and IRI-FS. Lower IRI-FS and IRI-PD scores were found to be significantly related to high suicide risk in depression.Conclusion: Based on our results, patients with major depressive disorder show significantly impaired empathy measures compared to the normal population. Our findings also suggest a close relationship between suicidality and empathy in patients with MDD.Keywords: Empathy, gender, hopelessness, major depressive disorder, suicide ÖZET Majör depresif bozukluğu olan hastalarda empati yanıtı ve klinik özelliklerle ilişkisiAmaç: Bildiğimiz kadarıyla majör depresif bozukluklu hastalarda empatik cevaplarla klinik özellikler arasındaki ilişkiyi araştıran herhangi bir çalışma yoktur. Amacımız majör depresif bozukluklu hastalarda duygusal ve bilişsel empati cevabını değerlendirmek ve empatinin klinik özelliklerle olan muhtemel ilişkisini araştırmaktır. Sonuç: Bulgularımıza dayanarak depresif bozukluklu hastalarda normal popülasyona göre anlamlı olarak bozulmuş empati ölçümleri olduğu söylenebilir. Ayrıca bulgularımız depresif olgularda intihar ve empati arasında yakın bir ilişki olduğuna işaret etmektedir.

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Section: Discussionsupporting

confidence: 92%

Relationship between empathic responding and its clinical characteristics in patients with major depressive disorder

Ekinci¹,

Ekinci²

2016

Dusunen Adam

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“…In previous studies conducted up to date in patients with mood disorders, the age was determined to not affect the Eyes test performance and this finding was interpreted as Eyes test' s being more related with the emotional domain than the cognitive functions. (31,32,33).…”

Section: Discussionmentioning

confidence: 99%

Theory of Mind and Selective Attention, Response Inhibition, Cognitive Flexibility in Patients with Schizophrenia

Eşsizoğlu

Köşger

Özaydin

et al. 2017

Arch Neuropsychiatr

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“…While the former system is obviously implicated in bipolar disorder, involvement of the ventral prefrontal system is also being increasingly recognized (55). Thus, tasks that probe the ventral system by measuring broader executive functions such as decision making (16), theory of mind (36,64), and self-regulation (39) are excluded from our analysis.…”

Section: Limitations and Future Directionsmentioning

confidence: 99%

Neuropsychological functioning in euthymic bipolar disorder: a meta‐analysis

Torres

Boudreau

Yatham

2007

Acta Psychiatr Scand

535

370

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IntroductionIt is well established that patients with bipolar disorder in acute manic-depressive states show considerable cognitive impairment (1-3). In recent years, however, there has been a strong shift towards studying neurocognitive functions in euthymic patients with bipolar disorder. These Torres IJ, Boudreau VG, Yatham LN. Neuropsychological functioning in euthymic bipolar disorder: a meta-analysis.Objective: Although cognitive deficits are prominent in symptomatic patients with bipolar disorder, the extent and pattern of cognitive impairment in euthymic patients remain uncertain. Method: Neuropsychological studies comparing euthymic bipolar patients and healthy controls were evaluated. Across studies, effect sizes reflecting patient-control differences in task performance were computed for the 15 most frequently studied cognitive measures in the literature. Results: Across the broad cognitive domains of attention ⁄ processing speed, episodic memory, and executive functioning, medium-to-large performance effect size differences were consistently observed between patients and controls, favoring the latter. Deficits were not observed on measures of vocabulary and premorbid IQ. Conclusion: Meta-analytic findings provide evidence of a trait-related neuropsychological deficit in bipolar disorder involving attention ⁄ processing speed, memory, and executive function. Findings are discussed with regard to potential moderators, etiologic considerations, limitations, and future directions in neuropsychological research on bipolar disorder.

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Deficiency of theory of mind in patients with remitted mood disorder

Cited by 187 publications

References 33 publications

Relationship between empathic responding and its clinical characteristics in patients with major depressive disorder

Relationship between empathic responding and its clinical characteristics in patients with major depressive disorder

Theory of Mind and Selective Attention, Response Inhibition, Cognitive Flexibility in Patients with Schizophrenia

Neuropsychological functioning in euthymic bipolar disorder: a meta‐analysis

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