Déficit acquis et répété en facteur VII au cours d'épisodes infectieux : à propos d'un cas

Acquired deficiency of coagulation factor VII

“…Acquired FVII deficiency, which is not associated with vitamin K deficiency, antagonists or hepatopathies, though rare, is correlated with the presence of different tumors, 1,4 the occurrence of sepsis, 5 antiphospholipid antibodies, 6 aplastic anemia 7 and hematopoietic stem cell transplantation. 8 …”

“…After the surgical removal of the myxoma, the PT normalized and the FVII activity level increased within the first 24 h after surgery. Bidet et al 5 described a 24-year-old patient with intra-abdominal septic focus who developed FVII deficiency, without evidence of inhibitors; the deficiency partially recovered only with the intravenous administration of vitamin K. With the resolution of sepsis, the patient's PT and FVII activity normalized. Lim et al 6 reported a 71-year-old patient with an expanding hematoma of the thoracic and abdominal walls, and prolonged APTT and PT.…”