Objective
To evaluate the effects of intravenous infusion of fluids and sodium on the
first day of admission on infusion of enteral nutrition in the first 5 days
in intensive care patients.
Methods
A prospective cohort study was conducted with critical nonsurgical patients
admitted for at least 5 days who were on mechanical ventilation and
receiving enteral nutrition. The amount of intravenous fluids and sodium
infused on the first day and the volume of enteral nutrition infused in the
first 5 days were investigated. The volume of intravenous fluids >
35mL/kg or ≤ 35mL/kg of body weight and sodium (above or below the
25th percentile) infused on the first day was compared with infused enteral
nutrition.
Results
A total of 86 patients were studied, with a mean (± standard
deviation) of 65 ± 17 years, of which 54.7% were female. On the first
day, 3,393.7 ± 1,417.0mL of fluid (48.2 ± 23.0mL/kg) and 12.2
± 5.1g of sodium were administered. Fifty-eight (67.4%) patients
received more than 35mL/kg of fluids. In 5 days, 67 ± 19.8% (2,993.8
± 1,324.4mL) of the prescribed enteral nutrition was received.
Patients who received > 35mL/kg of intravenous fluids also received less
enteral nutrition in 5 days (2,781.4 ± 1,337.9
versus
3,433.6 ± 1,202.2mL; p = 0.03)
versus
those who received ≤ 35mL/kg. Patients
with intravenous sodium infusion above the 25th percentile (≥ 8.73g)
on the first day received less enteral nutrition volume in 5 days (2,827.2
± 1,398.0
versus
3,509.3 ± 911.9mL; p =
0.02).
Conclusion
The results of this study support the assumption that the administration of
intravenous fluids > 35mL/kg and sodium ≥ 8.73g on the first day
of hospitalization may contribute to the lower infusion of enteral nutrition
in critically ill patients.