The digital twin has been used for decades in industries and in this last twenty years in the construction industry as a model that creates a connection between the physical systems and the digital systems. Thanks to IoT and AI, a static model evolves as a constantly updated system that is in connection with the real environment, thanks to data provided by sensors placed in it. In this paper the possibility of applying this system to complex infrastructures, such as port areas, is analysed. It has been chosen to apply it to a compact port area in order to be able to use this system, to investigate the different possibilities that it offers and to then be able to use it for larger port areas. The case study is located in the Ventotene Island, a small island located in the Tyrrhenian Sea, in front of the coast of central Italy, which is characterized by a considerable number of visitors during the summer season and a significantly reduced attendance during the rest of the year. It has been created an as-built digital model developed in BIM environment. It contains the architectural, structural and MEP models, both of port area and the building which is used for different services. Studies and simulations were carried out using the model, integrated with monitoring system to increase the security of the area. Finally, the model was connected to sensors installed in the real environment, obtaining the digital twin. Using this system, it is possible to achieve the control of facility management interventions, towards predictive maintenance, but also the control of the security and energy management, in order to verify the efficiency and the profitability of the operations and of the whole infrastructure.