Oral appliance therapy is a proven, effective treatment for obstructive sleep apnea (OSA) and snoring. With more than 54 million adults having OSA in the United States, dentists play an integral role in increasing access to care for those with undiagnosed and untreated OSA. These standards outline an approach to patient management that underscores the collaborative care that is necessary between dentists and physicians and provides guidance for patient examination, patient screening, treatment management, education, and followup care. Although this article provides best practices for dental sleep medicine as it currently exists, the fluid and dynamic nature of DSM should be recognized, with the understanding that periodic updates to these standards will be required.