Defining the Burden of Emergency General Surgery in Transplant Patients: A Nationwide Examination

Bhatti, Umar F.; Shah, Adil A.; Williams, Aaron M.; Zuberi, Maaz K.; Butt, Zoya; Biesterveld, Ben E.; Alam, Hasan B.; Idrees, Kamran

doi:10.1016/j.jss.2019.07.054

Cited by 3 publications

(3 citation statements)

References 24 publications

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“…In contrast to a study by Bhatti et al which found greater mortality in transplant recipients following EGS, the present work found that transplant status was not significantly associated with increased odds of mortality [ 24 ]. Interestingly, liver transplant recipients were observed to have lower odds of mortality and a number of other complications, including transplant-related complications, after adjustment.…”

Section: Discussioncontrasting

confidence: 99%

Clinical and financial outcomes of transplant recipients following emergency general surgery operations

Tran

Richardson

Bakhtiyar

et al. 2023

Surgery Open Science

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Section: Discussioncontrasting

confidence: 99%

Clinical and financial outcomes of transplant recipients following emergency general surgery operations

Tran

Richardson

Bakhtiyar

et al. 2023

Surgery Open Science

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“…However, these studies were limited to kidney transplant recipients, included mostly elective operations, lacked data on the indication for surgery, and excluded patients undergoing nonoperative management. [23][24][25][26] Improving our understanding of the impact of EGS conditions in this population is essential to the provision of high-quality care. The diagnosis of EGS conditions in SOTRs is challenging and delays in treatment may lead to worse outcomes.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Incidence and Mortality of Emergency General Surgery Conditions Among Solid Organ Transplant Recipients in Ontario, Canada: A Population-based Analysis

et al. 2022

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Background. Emergency general surgery (EGS) conditions and their outcomes are perceived to be disproportionately high among solid organ transplant recipients (SOTRs). However, this has not been adequately investigated at a population level. We characterized the incidence and mortality of EGS conditions among SOTRs compared with nontransplant patients. Methods. Data were collected through linked administrative population-based databases in Ontario, Canada. We included all adult SOTRs (kidney, liver, heart, and lung) who underwent transplantation between 2002 and 2017. We then identified posttransplantation emergency department visits for EGS conditions (appendicitis, cholecystitis, choledocolithiasis, perforated diverticulitis, incarcerated/strangulated hernias, small bowel obstruction, and perforated peptic ulcer). Age-, sex-, and year-standardized incidence rate ratios (SIRRs) were generated. Logistic regression models were used to evaluate association between transplantation status and 30 d mortality after adjusting for demographics, year, and comorbidities. Results. Ten thousand seventy-three SOTRs and 12 608 135 persons were analyzed. SOTRs developed 881 EGS conditions (non-SOTRs: 552 194 events). The incidence of all EGS conditions among SOTR was significantly higher compared with the nontransplant patients [SIRR 3.56 (95% confidence interval [CI] 3.32-3.82)], even among those with high Aggregated Diagnosis Groups scores (>10) [SIRR 2.76 (95% CI 2.53-3.00)]. SOTRs were 1.4 times more likely to die at 30 d [adjusted odds ratio 1.44 (95% CI 1.08-1.91)] after an EGS event compared with nontransplant patients, predominantly amongst lung transplant recipients [adjusted odds ratio 3.28 (95% CI 1.72-6.24)].Conclusions. The incidence of EGS conditions is significantly higher in SOTRs even after stratifying by comorbidity burden. This is of particular importance as SOTRs also have a higher likelihood of death after an EGS condition, especially lung transplant recipients.

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Accuracy of Risk Estimation for Surgeons Versus Risk Calculators in Emergency General Surgery

Huckaby

Dadashzadeh

et al. 2022

Journal of Surgical Research

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Defining the Burden of Emergency General Surgery in Transplant Patients: A Nationwide Examination

Cited by 3 publications

References 24 publications

Clinical and financial outcomes of transplant recipients following emergency general surgery operations

Clinical and financial outcomes of transplant recipients following emergency general surgery operations

Incidence and Mortality of Emergency General Surgery Conditions Among Solid Organ Transplant Recipients in Ontario, Canada: A Population-based Analysis

Accuracy of Risk Estimation for Surgeons Versus Risk Calculators in Emergency General Surgery

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