The aim of this study was to investigate whether treatment with minimally invasive transforaminal lumbar interbody fusion (Mis-TLIF) causes patients suffering from lumbar spinal stenosis (LSS) to experience less anxiety and better clinical efficacy than open transforaminal lumbar interbody fusion (TLIF).
Methods:In this retrospective cohort study, we analyzed 86 patients, including 46 male patients and 41 female patients, who suffered from single-segmental lumbar spinal stenosis in our department between January 2016 and January 2018. They were divided into two groups: a control group (n = 46), for patients who underwent open TLIF surgery, and an experimental group (n = 40), for patients who underwent Mis-TLIF surgery. All patients were evaluated based on operation time, intraoperative blood loss, hospital stay, visual analogue scale (VAS), Oswestry disability index (ODI), hospital anxiety depression scale (HADS), fusion rate, and complications (screw misplacement and loosening, cerebrospinal fluid leakage, infection, and delayed wound healing). Patient characteristics were compared within and between groups.
Results:The average incision length was 3.64 AE 0.476 cm in the experimental group, which was smaller than that (8.11 AE 2.406 cm) in the control group (P < 0.05). The operation time of the experimental group was a little longer than that of the control group. The intraoperative blood loss and hospital stay in the experimental group were less than those in the control group. The mean preoperative low back pain VAS score was 7.525 AE 1.432 in the experimental group and 7.087 AE 1.799 in the control group (P > 0.05). The low back pain VAS scores on postoperative day 3 and at 3, 6, and 12 months postoperatively were 5.000 AE 0.987, 4.075 AE 0.997, 2.150 AE 0.834, and 1.450 AE 0.639 in the experimental group, respectively; these scores were lower than those in the control group (6.870 AE 1.572, P < 0.05; 4.630 AE 1.103, P < 0.05; 2.630 AE 1.103, P < 0.05; and 2.326 AE 1.034, P < 0.05, respectively). There was no obvious difference in the leg pain VAS scores between the two groups at all follow-up points. The mean preoperative ODI score was 58.700% AE 19.703% in the experimental group and 61.696% AE 17.583% in the control group (P > 0.05). The ODI scores at postoperative months 3, 6, and 12 were 25.225% AE 5.554%, 20.150% AE 7.698%, and 16.125% AE 9.565% in the experimental group; these scores were lower than those in the control group (49.130% AE 14.805%, P < 0.05; 34.044% AE 15.148%, P < 0.05; and 29.282% AE 132.567%, P < 0.05, respectively).