Definition and aetiology of infective exacerbations of COPD

Updates in Chronic Obstructive Pulmonary Disease for the Year 2014

“…In a broad sense, two different approaches have been proposed about how COPD exacerbations should be defined. One of them based on symptoms alone (symptombased) and the other is based on symptoms plus an event such as the prescription of medication by healthcare providers or hospital admission for an acute exacerbation (eventbased) [26]. An expert panel definition is "a sustained worsening of the patient's condition from the stable state and beyond normal day-to-day variations that is acute in onset and may warrant additional treatment in a patient with underlying COPD" [26].…”

“…One of them based on symptoms alone (symptombased) and the other is based on symptoms plus an event such as the prescription of medication by healthcare providers or hospital admission for an acute exacerbation (eventbased) [26]. An expert panel definition is "a sustained worsening of the patient's condition from the stable state and beyond normal day-to-day variations that is acute in onset and may warrant additional treatment in a patient with underlying COPD" [26]. Several COPD studies have used the definition "a worsening of respiratory symptoms, which required treatment with oral corticosteroids and/or antibiotics" [24].…”

Acute exacerbation in COPD and asthma

“…Semptomatik tanımlamada "solunum semptomlarında tıbbi tedavi gerektirecek boyutta kötüleşmenin olması" ve daha sonra öne sürülen olaya dayalı atak tanımında "hastanın stabil durumunda günlük olağan değişikliklerin ötesinde ve hastanın altta yatan KOAH tedavisine ek tedavi gerektiren akut gelişen olaylar" temel alınmaktadır (2).…”