Definition of a spine fracture threshold based upon prospective fracture risk

Ross, Philip D.; Wasnich, Richard D.; Heilbrun, L. K.; Vogel, John M.

doi:10.1016/8756-3282(87)90001-9

Cited by 86 publications

(15 citation statements)

References 25 publications

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“…During the prospective follow-up no fractures occurred among those with high BMD values. These findings are in agreement with those of earlier prospective studies [2][3][4][5] indicating that BMD values of calcaneus provide useful information on the probability of fractures even for the very old.…”

Section: Discussionsupporting

confidence: 93%

“…Studies on different age groups have shown that appendicular bone mineral content (BMC) and density (BMD) such as that of the calcaneus can be used as a predictor of fractures [2][3][4][5], and that its predictive power is similar to that of other measurements made at the hip, spine and vertebra [4,5]. The overall risk of diverse types of fractures, such as fractures of the ribs, metacarpals and forearm, is highest among women who have the lowest bone mass in the radius and calcaneus [2,6].…”

Section: Introductionmentioning

confidence: 99%

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Bone density of the calcaneus and fractures in 75- and 80-year-old men and women

et al. 1994

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Bone mineral density of the calcaneus in relation to fractures was studied both retrospectively and prospectively among the 75- and 80-year-old men and women resident in the city of Jyväskylä, Finland, in 1989 and 1990, respectively. The bone measurements were performed at the calcaneus by 125I-photon absorption. Retrospective fracture (RF) history after age 50 was collected by questionnaire and interview, and reported fractures were checked from medical records. In the retrospective study, in the 75-year-olds a fracture was found in 22% (n = 22) of men and in 45% (n = 84) of women. The corresponding figures for the 80-year-olds were 16% (n = 9) and 35% (n = 48). Over half of the fractures were of the wrist/hand or ankle/leg. Prospective fractures (PF) were recorded over periods of 29-34 months. Twenty of the 75-year-olds and 16 of the 80-year-olds sustained a fracture during the follow-up period. In the 75-year-olds, the results showed that both RF and PF women, together with the RF men, had lower bone area density (BMDa) and volume density (BMDv) than the non-fracture (NF) subjects (p = 0.001-0.011). In the 80-year-olds, significantly lower BMDa was found in the RF women (p = 0.008) and lower BMDv in the PF women (p = 0.024) compared with the NF subjects. During the follow-up period there were no fractures in either of the sex or age groups among those with BMDa and BMDv values greater than 1 SD above the mean. (ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Bone density of the calcaneus and fractures in 75- and 80-year-old men and women

et al. 1994

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“…Several techniques are used to measure bone mass [3][4][5], but they do not measure bone quality. Some findings suggest that factors other than bone mass are also involved in the occurrence of fractures [6][7][8]. Alterations in the biomechanical properties of bone tissue such as loss of connectivity of bone trabeculae or inadequate repair of fatigue damage are examples of the importance of methods for measuring the quality of bone.…”

Section: Introductionmentioning

confidence: 97%

Bone status assessed by quantitative ultrasound in healthy postmenopausal Polish women: Normative data

Pluskiewicz

1998

Clin Rheumatol

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In this study, ultrasound measurements of the calcaneus of 712 healthy postmenopausal Polish women aged 50-85 years (mean age 59.5 years) were performed. Broadband ultrasound attenuation (BUA) and speed of sound (SOS) were obtained with a Lunar Achilles machine. The women in the study were volunteers evaluated at the Osteoporotic Centre for screening purposes. The results showed a decrease in ultrasound values within the age range 52-74 years for BUA (9.8%) and SOS (1.9%). Simple linear regression analysis showed a negative, significant correlation with age for BUA (r=-0.36) and SOS (r=-0.38). Years since menopause (YSM) showed significant correlations with BUA and SOS (r=-0.33 and -0.35, respectively). Using multiple regression analysis, the following equations were obtained: BUA=66.04 - 0.31Age + 0.06Weight - 0.18 YSM + 0.27Height + 0.52 Body mass index and SOS=1547.17 - 1.02Age + 0.38Weight - 0.48 YSM. Several weak, but significant, correlations between ultrasound values and weight, height and body mass were noted (r ranged from 0.09 to -0.29). A decrease of ultrasound values was expressed mainly in the first 6-10 years of the postmenopause period. The pattern of this decrease was similar to data published by other authors, but values in postmenopausal Polish women are slightly lower.

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“…Since bone mass is related to bone strength (Riggs et al 1981, Cummings 1989, it is important to identify persons with low bone mineral density (BMD) in the prevention of subsequent osteoporosis fractures, which rarely occur above certain levels of BMD (Riggs et al 1981, Grubb et al 1984, Ross et al 1987. Only 60% of the increase in hip fracture incidence can be accounted for by the increasing life expectancy of the population (Cummings 1989, Gullberg et al 1993.…”

mentioning

confidence: 99%

Bone mineral density assessed by quantitative ultrasound and dual energy X-ray absorptiometry: Normative data in Malmö, Sweden

Karlsson

Obrant

Nilsson

et al. 1998

Acta Orthopaedica Scandinavica

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Definition of a spine fracture threshold based upon prospective fracture risk

Cited by 86 publications

References 25 publications

Bone density of the calcaneus and fractures in 75- and 80-year-old men and women

Bone density of the calcaneus and fractures in 75- and 80-year-old men and women

Bone status assessed by quantitative ultrasound in healthy postmenopausal Polish women: Normative data

Bone mineral density assessed by quantitative ultrasound and dual energy X-ray absorptiometry: Normative data in Malmö, Sweden

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