Definition of “persistent vomiting” in current medical literature

Morra, Mostafa Ebraheem; Elshafay, Abdelrahman; Kansakar, Aswin Ratna; Mehyar, Ghaleb Muhammad; Dang, Nguyen Phan Hoang; Mattar, Omar Mohamed; Iqtadar, Somia; Mostafa, Mostafa Reda; Vu-Ngoc, Hai; Vu, Tran Le Huy; Ghazy, Ahmed; Kaboub, F.; Huy, Nguyen Tien; Hirayama, Kenji

doi:10.1097/md.0000000000008025

Cited by 5 publications

(4 citation statements)

References 26 publications

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“…Nausea is defined as an unpleasant sensation of needing to vomit, which can be accompanied by autonomic symptoms such as salivation, pallor, tachycardia and hidrosis [ 18 ]. Vomiting is the ejection of the contents from the stomach through the mouth [ 19 ]. Pruritus is defined as severe itching of the skin coupled with the desire to scratch [ 20 ].…”

Section: Methodsmentioning

confidence: 99%

Intrathecal Morphine and Post-Operative Pain Relief in Robotic Surgeries: A Systematic Review and Meta-Analysis

Tee,

Tsoi,

Lee

et al. 2023

JCM

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Despite the potential benefits of intrathecal morphine (ITM), the precise role and dosing of ITM in robotic assisted surgery (RAS) remains unclear. This systematic review explores real-world evidence to evaluate the efficacy and outcomes of ITM in patients undergoing RAS. In accordance with PRISMA guidelines, a comprehensive search was conducted on four databases: MEDLINE, Embase, Cochrane Library and APA PsycInfo. Primary outcomes included pain scores at rest and on exertion at 24- and 48-h time intervals, and secondary outcomes aimed to explore the side effects of ITM. A meta-analysis was conducted to determine mean differences. A risk of bias assessment was conducted via the Cochrane Risk of Bias 2 tool. A total of 9 RCTs involving 619 patients were included in this review, of which 298 patients were administered ITM. Significant pain score reductions were observed both at rest (MD = −27.15; 95% CI [−43.97, −10.33]; I2 = 95%; p = 0.002) and on exertion (MD = −25.88; 95% CI [−37.03, −14.72]; I2 = 79%; p = 0.0003) 24 h postoperatively in the ITM groups, accompanied by a notable decrease in postoperative IV morphine equivalent consumption at 24 h (MD = −20.13; 95% CI [−30.74, −9.52]; I2 = 77%; p = 0.0002). ITM improved pain scores both at rest and on exertion at 24 and 48 h intervals, concurrently reducing the need for postoperative opioid consumption, but at the cost of an increased incidence of adverse events.

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Section: Methodsmentioning

confidence: 99%

Intrathecal Morphine and Post-Operative Pain Relief in Robotic Surgeries: A Systematic Review and Meta-Analysis

Tee,

Tsoi,

Lee

et al. 2023

JCM

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“…1 Severe persistent vomiting defined as several daily episodes for the past 2 or more consecutive days 31 with no evidence of esophagitis or GUE 2 IRIS CKD stage 4 with no evidence of GUE 3 Gastric, intestinal (excluding small cell lymphoma), pancreatic neoplasia with no evidence of GUE 4 Microcytosis or discordant blood urea nitrogen:creatinine ratio, but mild anemia with concomitant renal disease 5 Thrombocytopenia or coagulopathy-induced GI bleeding 6 Pre-or post-coil embolization for intrahepatic portosystemic shunts 3 = Gastroprotectant therapy was not indicated for the following diseases or scenarios in the absence of evidence for GUE (see item 1a, 1 for evidence of GUE) or esophagitis (see item 1a, 2 for evidence of esophagitis):…”

Section: Indications and Appropriateness Of Gastroprotectant Prescrip...mentioning

confidence: 99%

Evaluation of gastroprotectant administration in hospitalized cats in a tertiary referral hospital

Ullal,

Marks,

Evenhuis

et al. 2023

Journal of Feline Medicine and Surgery

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Objectives The primary objective of this study was to evaluate the prescription patterns and appropriateness of the use of gastroprotectant medication in cats. Methods Pharmacy dispensation logs from an academic tertiary referral center were reviewed between 1 January 2018 and 31 December 2018. Cats that were administered proton pump inhibitors (PPIs), histamine-2 receptor antagonists (H2RAs), sucralfate, misoprostol, antacids or a combination were included. Data regarding medication, dosage, formulation, duration of administration, completeness of discharge instructions and clinical rationales for administration were obtained from medical records. The appropriateness of gastroprotectant use was assessed according to the American College of Veterinary Internal Medicine consensus statement guidelines. Results Of the 110 cases, 67 (60.9%) were prescribed a gastroprotectant medication without an appropriate indication. The most common reason for prescription was acute kidney injury in 26/67 (38.8%). PPIs were the most common gastroprotectant medication administered in 95/110 (86.3%) cats, followed by sucralfate in 18/110 (16.4%) and H2RAs in 11/110 (10%). Of the 35 cases in which gastroprotectant therapy was indicated, the medication chosen or dosage administered was considered suboptimal in 16 (45.7%). Instructions regarding the duration of administration, potential adverse effects and timing of administration in relation to meals or other medications were inconsistently provided in discharge instructions to pet owners. Of the 29 cases discharged with omeprazole, only 13 (44.8%) instructions included a duration of administration, while 6 (20.7%) recommended continuing gastroprotectants indefinitely until further notice, 16 (55.2%) discussed the timing of the administration in relation to a meal and six (20.7%) mentioned potential adverse effects; none advised tapering of omeprazole before discontinuation. Conclusions and relevance When prescribed, gastroprotectant medications were frequently prescribed injudiciously to cats in this referral population over a 12-month period. Discharge instructions to pet owners also often lacked information and recommendations regarding optimal administration, potential adverse effects, and tapering or discontinuation of the medications.

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“…Emesis is a reflex which integrates a complex set of actions of the inspiratory and expiratory muscles in order to produce an involuntary, forceful expulsion of the contents of stomach through the mouth and rarely through the nose [1]. Emesis must be distinguished from regurgitation and rumination.…”

Section: Introductionmentioning

confidence: 99%

“…Disorders of Brain-Gut Interactions (DBGI) is the new name of FGID and the diagnosis is mainly clinical [1][2][3]. Emesis J Gastrointestin Liver Dis, September 2019 Vol.…”

Section: Introductionmentioning

confidence: 99%

Functional Emesis

Popa

Chiarioni

David

et al. 2019

JGLD

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Background: Emesis is an essential survival response, because consumption of food is a key element in the survival behavior and the act of feeding can expose the majority of internal organs to toxins, altered food, viruses, bacteria or fungi. The relationship between visceral or vestibular stimuli and the anatomical structures of the brain-gut axis explain the modulation of the gastrointestinal response. We aimed to review comprehensively the current knowledge on emesis occurring in the disorders of brain-gut interaction (DBGI), i.e. functional conditions presenting with emesis. Methods: PubMed, Cochrane Library, EMBASE and WILEY databases were screened for relevant publications from the last 20 years regarding brain-gut disorders manifesting emesis. We included in the search also idiopathic gastroparesis, as a condition paralleling the postprandial distress syndrome. Results: We critically analyzed 2 articles about chronic nausea and vomiting syndrome, 9 articles about cyclic vomiting syndrome, 9 articles about cannabinoid hyperemesis, 10 articles about idiopathic gastroparesis and 6 articles about gastroparesis like-syndrome. Contradictory results regarding the implication of environmental factors in the development of emesis in DBGI demonstrate that the underlying pathogenesis is still not completely understood.

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Definition of “persistent vomiting” in current medical literature

Cited by 5 publications

References 26 publications

Intrathecal Morphine and Post-Operative Pain Relief in Robotic Surgeries: A Systematic Review and Meta-Analysis

Intrathecal Morphine and Post-Operative Pain Relief in Robotic Surgeries: A Systematic Review and Meta-Analysis

Evaluation of gastroprotectant administration in hospitalized cats in a tertiary referral hospital

Functional Emesis

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