This thesis is focused on understanding the deformation and failure mechanisms in incremental sheet forming (ISF) and on development of effective and efficient closed-loop control strategies to delay the fracture in multi-point ISF. Incremental sheet forming is a flexible and energy-efficient rapid prototyping process for production of small-batch and customized functional sheet components. The innovation of ISF is to achieve higher formability, flexibility and process control with localized plastic deformation compared with traditional sheet metal forming processes. Multi-point incremental forming (MPIF) shows higher formability and geometric accuracy than single point incremental forming (SPIF) and has attracted interest from industry currently. In the past decades, the industry application of multi-point ISF is still limited due to the limitation of formability, especially for producing parts with complex geometric features. Experimental and numerical ISF studies show that the formability in ISF can be improved by altering some critical process parameters. However, most of the proposed methodologies are either component specific or are based on trial-and-error approaches, while limited work has been published on closed-loop feedback control strategies for formability improvement in multi-point ISF. The first research objective of this thesis is the deformation mechanism and formability investigation in multi-point ISF. The aim of this study is to identify the contribution of different deformation modes and lay a foundation of developing damage model-coupled numerical simulation for fracture prediction in multi-point ISF. To this end, a full-scale three-dimensional numerical simulation with solid finite elements is developed. The deformation modes in different layers at different contact zones along different directions are investigated and discussed in detail. It is indicated that the existence of the supporting die leads to an increase of the hydrostatic pressure and the through-thethickness shear strain, and a decrease of the stress gradient in the thickness direction in the doublesided contact zone, which may lead to smaller springback and slow the damage accumulation rate in multi-point ISF. The second objective of this thesis is focused on the fracture prediction in multi-point ISF. In particular, six damage models are coded into finite element models through ABAQUS/VUMAT subroutine and a numerical comparative study is conducted for fracture prediction in multi-point ISF with a free-formed ellipsoid shape under different loading conditions. It is indicated that the Ayada model could predict the fracture location and fracture depth more accurately than others, however, it is also found that the fracture location and fracture depth cannot be accurately predicted simultaneously with the investigated damage models in this study. In addition, it can be found that Publications included in this thesis No publications included.