Deformation and fracture of polystyrene/polypropylene blends: A simulation study

Deng, Shengwei; Zhao, Xuezhe; Huang, Yongmin; Han, Xia; Liu, Honglai; Hu, Ying

doi:10.1016/j.polymer.2011.09.050

Cited by 33 publications

(16 citation statements)

References 27 publications

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“…It has been reported that gel thickness less than 20 µm lead to stiffness reaching that of the underlying substrate 34 . We next produced “hard” substrates by coating polystyrene (Young’s modulus of ≈3 GPa) 35 with thin films of Matrigel 2.9 ± 0.1 µm thick by evenly spreading 10 µL per cm 2 of substrate (Supplementary Information and Fig. S1).…”

Section: Resultsmentioning

confidence: 99%

Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function

Altay

Larrañaga

Tosi

et al. 2019

Sci Rep

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Intestinal organoids have emerged as a powerful in vitro tool for studying intestinal biology due to their resemblance to in vivo tissue at the structural and functional levels. However, their sphere-like geometry prevents access to the apical side of the epithelium, making them unsuitable for standard functional assays designed for flat cell monolayers. Here, we describe a simple method for the formation of epithelial monolayers that recapitulates the in vivo -like cell type composition and organization and that is suitable for functional tissue barrier assays. In our approach, epithelial monolayer spreading is driven by the substrate stiffness, while tissue barrier function is achieved by the basolateral delivery of medium enriched with stem cell niche and myofibroblast-derived factors. These monolayers contain major intestinal epithelial cell types organized into proliferating crypt-like domains and differentiated villus-like regions, closely resembling the in vivo cell distribution. As a unique characteristic, these epithelial monolayers form functional epithelial barriers with an accessible apical surface and physiologically relevant transepithelial electrical resistance values. Our technology offers an up-to-date and novel culture method for intestinal epithelium, providing an in vivo -like cell composition and distribution in a tissue culture format compatible with high-throughput drug absorption or microbe-epithelium interaction studies.

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Section: Resultsmentioning

confidence: 99%

Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function

Altay

Larrañaga

Tosi

et al. 2019

Sci Rep

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“…According to the theory of polymer strength [44][45][46], the entanglement of branching structures increases the molecular interaction and decreases the molecular slippage. For the tensile, flexural, and impact testing, the yield of linear iPP was caused by the breakage of chemical bonds and failure of Van der Waals forces.…”

Section: Mechanical Behaviormentioning

confidence: 99%

Relationship between molecular structure, crystallization behavior, and mechanical properties of long chain branching polypropylene

et al. 2016

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The crystallization behaviors and mechanical properties of both linear isotactic polypropylene (iPP) and long chain branching polypropylene (LCBPP) were investigated with differential scanning calorimetry, polarized optical microscopy, and wide-angle X-ray diffraction. The results indicated that the long chain branching (LCB) structure could act as nucleating agent accelerating the nucleation but impeding the crystal growth of LCBPP, and eventually increased the crystallization peak temperature and decreased the spherulite size of LCBPP. Moreover, with the presence of LCB structure, b-form polypropylene was generated in LCBPPs under injection molding conditions, and the content of b-form increased with the increasing of LCB structure content. Benefiting from the combined effect of the LCB structure and b-form crystal, the LCBPPs revealed not only outstanding toughness but also desired stiffness. The impact strength, flexural modulus and tensile strength of HMSPP3 were increased by, respectively, 260.0, 54.7, and 17.2 % than those of linear iPP. These results are helpful to develop new types of high performance polypropylene.

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“…More detailed description about the fracture process can be found in our previous work. 14,29 C. Viscoelastic LSM for studying stress relaxation…”

Section: B Lattice Spring Model For Simulating Elastic Deformation Amentioning

confidence: 99%

Mechanical properties of high-performance elastomeric nanocomposites: a sequential mesoscale simulation approach

Deng

Huang

et al. 2014

RSC Adv.

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The incorporation of nanoparticles into elastomeric block copolymers affords engineers an opportunity to obtain polymer nanocomposites that potentially rival the most advanced materials in nature. A computationally efficient simulation method that utilized MesoDyn for the morphologies and the lattice spring model (LSM) for the mechanical properties was adopted in this work. The simulation results show that the selective distribution of nanoparticles in hard or soft segment microdomains of block copolymers will narrow the phase domain size in bicontinuous structures. The Zener model was incorporated into pure elastic LSM to capture the stress relaxation behavior. Mechanical tests reveal that the stress transfer between the polymer matrix and nanoparticles in different composites is critical to the stiffness enhancement. In dispersed structures, adding nanoparticles in a hard microdomain can increase the elastic modulus and maintain high extensibility without impairing its viscosity dramatically. The methods developed in this work yield guidelines for formulating elastomeric nanocomposites with desired macroscopic mechanical responses.

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Deformation and fracture of polystyrene/polypropylene blends: A simulation study

Cited by 33 publications

References 27 publications

Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function

Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function

Relationship between molecular structure, crystallization behavior, and mechanical properties of long chain branching polypropylene

Mechanical properties of high-performance elastomeric nanocomposites: a sequential mesoscale simulation approach

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