Experimental rock deformation has demonstrated that the strength of quartz is significantly reduced by the presence of intracrystalline H 2 O either bonded to the crystal lattice or occurring as micro-fluid inclusions, that is, quartz exhibits hydrolytic weakening (Ave Lallemant & Carter, 1971;Griggs, 1967;Griggs & Blacic, 1965;Tullis & Yund, 1980). Results from laboratory experiments established that hydrolytic weakening occurs in both synthetic and natural quartz crystals with intracrystalline H 2 O contents larger than 20-30 wt ppm (about 150 H/10 6 Si; Stünitz et al., 2017 and references therein). Several different microphysical processes have been proposed to explain hydrolytic weakening in quartz: (a) hydrolyzation of Si-O-Si bonds around dislocations, consequently decreasing the resistance to dislocation motion (i.e., reducing the Peierls stress; Griggs, 1967), (b) enhanced dislocation generation around H 2 O clusters within the crystal lattice (McLaren et al., 1989;Stünitz et al., 2017), and (c) enhanced recovery through increased ionic diffusivities and faster dislocation climb (Post et al., 1996;Tullis & Yund, 1989). Hydrolytic weakening has been experimentally observed in natural and synthetic quartz deformed at high homologous temperature, conditions for which dislocation climb and recovery processes control the overall strain rate (