Deformation of human abdominal aorta at biaxial tensioning

Investigation on the Behavior of κ ‐Carrageenan Hydrogels for Compressive Intra‐Vessel Disintegration

“…[ 35 ] Thus, comparing a single aorta wall with a double‐walled vas deferens renders a similar thickness of the structures. [ 18,35 ]…”

“…The use of tensile aortae stresses for VD compression stress suffers the following problems: –compressive stress is assumed isotropic through different tensile moduli for axial and radial tensions are reported [ 18 ] –we neglect the differences in histology of human abdominal aortae and VD –stress–strain curves are exponential for aortae (Figure 1) –calculation of the compressive modulus from the tensile modulus is only valid within the linear response of materials: E = 3K(1−2ν), where E is the tensile modulus, K the compressive one and ν the Poisson ratio –assuming incompressibility, the bulk modulus is infinite –the Poisson ratio was assumed 0.5, [ 36 ] though it is usually undetermined for human aortae, as VD …”

“…From the magnitude of tissue shear stiffening and hydrogel behavior, it can be concluded that hydrogels matrices at low biopolymer concentrations will break before tissue damage occurs. [ 17,18 ] This can be a possible approach for the disintegration of hydrogels in tissue engineering. Compression of the hydrogels would result in loss of the matrix integrity and thereby the stabilizing or occluding effects while surrounding tissues would be mostly unaffected by compressive or massaging treatments.…”