Degradable carrier-free spray hydrogel based on self-assembly of natural small molecule for prevention of postoperative adhesion

Zou, Linjun; Hou, Yong; Zhang, Jiawen; Chen, Meiying; Wu, Peixuan; Feng, Chao; Li, Qinglong; Xu, Xudong; Sun, Zhaocui; Ma, Guoxu

doi:10.1016/j.mtbio.2023.100755

Materials Today Bio

2023

DOI: 10.1016/j.mtbio.2023.100755

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Degradable carrier-free spray hydrogel based on self-assembly of natural small molecule for prevention of postoperative adhesion

Linjun Zou

Yong Hou

Jiawen Zhang

et al.

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Cited by 6 publications

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Natural Products from Herbal Medicine Self‐Assemble into Advanced Bioactive Materials

Guo,

Luo,

et al. 2024

Advanced Science

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Novel biomaterials are becoming more crucial in treating human diseases. However, many materials require complex artificial modifications and synthesis, leading to potential difficulties in preparation, side effects, and clinical translation. Recently, significant progress has been achieved in terms of direct self‐assembly of natural products from herbal medicine (NPHM), an important source for novel medications, resulting in a wide range of bioactive supramolecular materials including gels, and nanoparticles. The NPHM‐based supramolecular bioactive materials are produced from renewable resources, are simple to prepare, and have demonstrated multi‐functionality including slow‐release, smart‐responsive release, and especially possess powerful biological effects to treat various diseases. In this review, NPHM‐based supramolecular bioactive materials have been revealed as an emerging, revolutionary, and promising strategy. The development, advantages, and limitations of NPHM, as well as the advantageous position of NPHM‐based materials, are first reviewed. Subsequently, a systematic and comprehensive analysis of the self‐assembly strategies specific to seven major classes of NPHM is highlighted. Insights into the influence of NPHM structural features on the formation of supramolecular materials are also provided. Finally, the drivers and preparations are summarized, emphasizing the biomedical applications, future scientific challenges, and opportunities, with the hope of igniting inspiration for future research and applications.

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Natural Products from Herbal Medicine Self‐Assemble into Advanced Bioactive Materials

Guo,

Luo,

et al. 2024

Advanced Science

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Investigation of the Effects of Boric Acid against Post Operative Testicular Adhesion Caused by Experimental Laporotomy in Rats

BOLAT,

KİLİÇLİOĞLU

et al. 2024

Biol Trace Elem Res

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Sprayable and self-healing chitosan-based hydrogels for promoting healing of infected wound via anti-bacteria, anti-inflammation and angiogenesis

Tan,

Xu,

Liu

et al. 2024

Carbohydrate Polymers

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Degradable carrier-free spray hydrogel based on self-assembly of natural small molecule for prevention of postoperative adhesion

Cited by 6 publications

References 74 publications

Natural Products from Herbal Medicine Self‐Assemble into Advanced Bioactive Materials

Natural Products from Herbal Medicine Self‐Assemble into Advanced Bioactive Materials

Investigation of the Effects of Boric Acid against Post Operative Testicular Adhesion Caused by Experimental Laporotomy in Rats

Sprayable and self-healing chitosan-based hydrogels for promoting healing of infected wound via anti-bacteria, anti-inflammation and angiogenesis

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