2018
DOI: 10.3390/coatings8110375
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Degradation and In Vivo Response of Hydroxyapatite-Coated Mg Alloy

Abstract: Nowadays there is a need for new generation of biodegradable implants, which should be able to stimulate the healing responses of injured tissues at the molecular level. Magnesium alloys attract great attention as perspective bone implants due to their biocompatibility, physical properties and ability to degrade completely under physiological conditions. The main purpose of this research was assessment of in vitro corrosion and surface morphology after short term in vivo implantation of Mg based implant covere… Show more

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Cited by 25 publications
(20 citation statements)
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“…The ratio of total surface area to Tris–SBF-27 solution volume was 10 mm 2 mL −1 at pH 7.4 and 37 °C for each disk-shaped sample. The solution was refreshed every 24 h to ensure constant initial chemical composition [ 27 ]. The pH value of the solution was measured daily for a group of samples without refreshing.…”
Section: Methodsmentioning
confidence: 99%
“…The ratio of total surface area to Tris–SBF-27 solution volume was 10 mm 2 mL −1 at pH 7.4 and 37 °C for each disk-shaped sample. The solution was refreshed every 24 h to ensure constant initial chemical composition [ 27 ]. The pH value of the solution was measured daily for a group of samples without refreshing.…”
Section: Methodsmentioning
confidence: 99%
“…The reaction products formed and precipitated on the surface of the samples. The degradation mechanism of magnesium in aqueous solution can be presented as the following reactions [22]:…”
Section: Corrosion Behavior Of the Sr-ha Sr-tcp Coatings And Uncoatementioning
confidence: 99%
“…The rate of coatings dissolution and their biological properties depend on the substances that the coatings are consisted of. The most common biocoatings are based on the calcium orthophosphates such as hydroxyapatite (HA) [22,25,27,40] and tricalcium phosphate (TCP) [34] or include their combinations. Hydroxyapatite has the lowest dissolution rate in body fluids.…”
Section: Introductionmentioning
confidence: 99%
“…The top CaPh coatings offer the resistance of the initial immersion period [47]. However, as mentioned above, the corrosion resistance of a single CaPh coating is inadequate for long-term immersion in SBF due to the loose structure and the dissolution of CaPh compounds.…”
Section: Corrosion Behaviour Of Pre-treated and Caph-coated Samples Imentioning
confidence: 99%