Degradation of Doxycycline, Enrofloxacin, and Sulfamethoxypyridazine under Simulated Sunlight at Different pH Values and Chemical Environments

Álvarez-Esmorís, Cristina; Rodríguez-López, Lucía; Fernández‐Calviño, David; Núñez‐Delgado, Avelino; Álvarez‐Rodríguez, Esperanza; Arias‐Estévez, Manuel

doi:10.3390/agronomy12020260

Cited by 5 publications

(3 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Specifically, the zwitterion and negatively charged forms grow as the pH increases (Figure 2), which is determined by their pK a values. The effect of increasing photo-degradation with rising pH has also been highlighted for other antibiotics, such as tetracyclines (Conde-Cid et al, 2018a), sulfonamides (Canonica et al, 2008;Conde-Cid et al, 2018b) and other families of antibiotics (Canonica et al, 2008;Rodríguez-López et al, 2021;Álvarez-Esmorís et al, 2022).…”

Section: Effect Of Ph On Amx and Azt Photo-degradationmentioning

confidence: 99%

Influence of pH, Humic Acids, and Salts on the Dissipation of Amoxicillin and Azithromycin Under Simulated Sunlight

Rodríguez-López¹,

Santás-Miguel²,

Núñez‐Delgado³

et al. 2022

Span. J. Soil Sci.

Self Cite

View full text Add to dashboard Cite

This work is focused on the study of the dissipation of the antibiotics amoxicillin (AMX) (an amino penicillin) and azithromycin (AZT) (belonging to the macrolide group), performed at a laboratory scale, under simulated sunlight and in the dark, at pH values 4.0, 5.5, and 7.2, and in the presence of humic acids and different inorganic salts. The results indicate that AMX is more affected than AZT by simulated sunlight, with half-lives ranging 7.7–9.9 h for AMX and 250–456 h for AZT. The lowest half-life values were obtained at pH 7.2 for AMX (7.7 h) and at pH 4.0 for AZT (250 h). Regarding the effect of various salts, the presence of NaNO3 causes that C/C0 decreases from 0.6 to 0 under simulated sunlight, having no effect on the dissipation of AMX in the dark. However, in the presence of FeCl3 at concentrations of 500 mg L−1, AMX suffered total dissipation, both under simulated sunlight and in the dark. For AZT the influence was lower, and the salts that caused a higher increase in its dissipation were NaCl (with C/C0 decreasing from 0.5 to 0.2) and CaCl2 (C/C0 decreasing from 0.5 to 0.3). The presence of humic acids caused a slight increase in the dissipation of AMX, both under simulated sunlight and in the dark, a fact that was attributed to the adsorption of the antibiotic onto these organic substances, which, however, caused a more marked increase in the dissipation of AZT (reaching 68%) under simulated sunlight. The overall results of this research can be considered clearly relevant, mainly to determine the fate of AMX and AZT when these antibiotics reach the environment as pollutants, either as regards their exposure to natural sunlight, or in relation to the use of inactivation/photo-degradation systems in decontamination procedures focused on environmental compartments.

show abstract

Section: Effect Of Ph On Amx and Azt Photo-degradationmentioning

confidence: 99%

Influence of pH, Humic Acids, and Salts on the Dissipation of Amoxicillin and Azithromycin Under Simulated Sunlight

Rodríguez-López¹,

Santás-Miguel²,

Núñez‐Delgado³

et al. 2022

Span. J. Soil Sci.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Adding to that the DOX state in acidic pH results in the existence of 45(%) of zwitterionic DOX 0 and 55(%) of cationic DOX + as shown in Figure 6. Thus, DOX is easily excited electronically by the illumination source [48]. Figure 6.…”

Section: Solar Photo-fenton (Spf) At Optimum Conditionsmentioning

confidence: 99%

“…The DOX concentration declined from 0.06 mM to 0.0066 mM at 350 nm with a DOX removal of 88.44%, which is in agreement with the results of previous studies on Figure 6. DOX speciation at different pH [48].…”

Section: Solar Photo-fenton (Spf) At Optimum Conditionsmentioning

confidence: 99%

Doxycycline Removal by Solar Photo-Fenton on a Pilot-Scale Composite Parabolic Collector (CPC) Reactor

Bensaibi,

Chabani,

Bouafia

et al. 2023

Processes

View full text Add to dashboard Cite

In this study, the solar photo-Fenton (SPF) process was investigated for the degradation of doxycycline (DOX) using a solar compound parabolic collector (CPC) reactor and a borosilicate serpentine tube with an irradiated volume of 1.8 L. The influence of the operating parameters, such as H2O2, Fe2+ dosage, and DOX concentration, was investigated. The optimum H2O2, Fe2+ dosage, and DOX concentration were found to be 4, 0.1, and 0.06 mM, respectively. The results of photo-Fenton experiments fitted the pseudo-first-order kinetic equation (R2 = 0.99). The efficiency of the treatment under optimized conditions was analyzed by an HPLC analysis of the samples, chemical oxygen demand (COD), and total organic carbon (TOC). The results obtained showed that the solar photo-Fenton process achieved a DOX degradation of 95.07%, a COD elimination of 81.43%, and a TOC elimination of 73.05%. The phytotoxicity tests revealed a 73.32% decrease in the germination index of watercress seeds, demonstrating that the SPF process minimizes the toxicity of the chemical and did not have any negative impact on plant growth. Overall, the results of this study suggest that SPF is a promising technology for the removal of doxycycline from wastewater.

show abstract

Electrochemical Treatment of Doxycycline-Containing Wastewater from Pharmaceutical Industry in Batch and Once-Through Continuous Mode

Dehariya,

Rajoria,

Sangal

2024

J. Electrochem. Soc.

View full text Add to dashboard Cite

Doxycycline (DOXY), a widely used antibiotic during COVID-19, was overused, leading to concerns about contamination of aquatic environments and environmental problems. The present study used the Ti/TiO2-RuO2-IrO2 electrode for DOXY's electrochemical oxidation (EO) in batch and once-through continuous mode operations. Process parameters were optimized using a response surface methodology (RSM)-Box-Behnken Design (BBD) model. The impact of key input parameters, including time (t), current density (j) (mA/cm2), and pH, on the percentage of DOXY degradation and energy consumption was systematically investigated. Under optimal conditions pH = 3, t = 73 min, and j = 11.63 mA/cm2, DOXY degradation achieved 91% with an energy consumption of 5.283 kWh/m³. In the once-through continuous mode EO process, optimal conditions reached 91% DOXY degradation with an energy consumption of 13.98 kWh/m³, achieved at a residence time (Rt) of 139 min, elapsed (Et) time of 100 min and at j = 20.40 mA/cm2. The EO process utilizing Ti/TiO2-RuO2-IrO2 electrodes demonstrates significant potential for the degradation of DOXY, primarily due to its enhanced degradation efficiency. This method's superior performance highlights its viability as a highly effective approach for the treatment of DOXY-contaminated wastewater.

show abstract

Degradation of Doxycycline, Enrofloxacin, and Sulfamethoxypyridazine under Simulated Sunlight at Different pH Values and Chemical Environments

Cited by 5 publications

References 35 publications

Influence of pH, Humic Acids, and Salts on the Dissipation of Amoxicillin and Azithromycin Under Simulated Sunlight

Influence of pH, Humic Acids, and Salts on the Dissipation of Amoxicillin and Azithromycin Under Simulated Sunlight

Doxycycline Removal by Solar Photo-Fenton on a Pilot-Scale Composite Parabolic Collector (CPC) Reactor

Electrochemical Treatment of Doxycycline-Containing Wastewater from Pharmaceutical Industry in Batch and Once-Through Continuous Mode

Contact Info

Product

Resources

About