PURPOSE. To investigate visual function in eyes with three subtypes of waterclefts (WCs). Kanazawa Medical University Hospital (2013-2017 and participants of Monzen Eye Study (2013)(2014)(2015)(2016), 77 transparent lenses, mean age 66.7 years, and 70 eyes with only WC opacity of 70 patients, mean age 68.1 years, divided into peripheral-, central-, and total-type WC groups, were analyzed. Opacity was classified by one ophthalmologist using slit-lamp microscopy. Corrected-distance visual acuity (CDVA), contrast visual acuity (CVA), spherical equivalent (SE), astigmatism values, corneal refractive power (CP), axial length (AL), straylight, backward light scattering (BLS), and higher order aberrations (HOA) were measured and lenticular refractive power (LP) was calculated based on the values of AL, CP, and SE.
METHODS. Of patients inRESULTS. Central-type WC showed significant decrease in CDVA and CVA and increase in straylight compared with control. Total-type WC showed significant decreases in CDVA, CVA, and LP, and increase in straylight, compared with control and peripheral-type WC. Total-and central-type WCs had significantly higher ocular total HOA and total-type WC had significantly higher internal total HOA than control. HOA correlated positively with CDVA (P < 0.001) and straylight (P ¼ 0.020), and CDVA negatively with straylight in eyes with WCs (P ¼ 0.008).CONCLUSIONS. Total-type WC was associated with decreased LP, causing hyperopia, decreased CDVA and higher straylight; thus, such lenticular change should be considered for surgery indication. Significant correlations between HOA and both CDVA and straylight suggested increased HOA may decrease visual function in eyes with WCs.
3652This work is licensed under a Creative Commons Attribution 4.0 International License. Downloaded from iovs.arvojournals.org on 07/09/2020 FIGURE 4. Correlations among visual acuity, straylight, and higher-order aberration in eyes with WCs. (a) Correlation between HOA and CDVA. (b) Correlation between HOA and straylight. (c) Correlation between straylight and CDVA. Pearson's correlation coefficient in linear regression.