Del macro al microcarcinoma tiroideo: cambios en las características de presentación del cáncer de tiroides en un centro universitario chileno en 20 años

Mosso, Lorena; Campusano, Claudia; González, Hernán; Domínguez, José Miguel; Salman, Patricio; Suazo, Valeria; Solar, Antonieta; Cerda, Jaime

doi:10.4067/s0034-98872013000400004

Cited by 4 publications

(1 citation statement)

References 13 publications

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“…Discusión En ecografía, el hallazgo de microcalcificaciones en un nódulo tiroideo es un signo de alta sospecha de cáncer tiroideo, fundamentalmente CPT 1,2 , la variedad más frecuente de cáncer tiroideo 12 , especialmente si se asocian a composición solida e hipoecogenicidad. Su presencia casi invariablemente va a ser motivo para indicar una PAF que por el momento es la mejor manera de avanzar en el diagnóstico.…”

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Microcalcificaciones y focos ecogénicos puntiformes, ¿qué tan bien sabemos lo que estamos viendo?

et al. 2017

Rev. chil. radiol.

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IntroducciónEn ecografía, las microcalcificaciones en nódulos tiroideos y su relevancia para el diagnóstico ha sido ampliamente estudiada, existiendo una asociación fuerte entre su presencia y el riesgo de malignidad, en especial, en relación al cáncer papilar de tiroides (CPT) 1, 2 . Desde un punto de vista anatomopatológico, se considera que representan la presencia de cuerpos de psammoma (CPs) (Figura 1) 3 .Microcalcificaciones y focos ecogénicos puntiformes, ¿qué tan bien sabemos lo que estamos viendo?

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Microcalcificaciones y focos ecogénicos puntiformes, ¿qué tan bien sabemos lo que estamos viendo?

et al. 2017

Rev. chil. radiol.

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Neck Sonography and Suppressed Thyroglobulin Have High Sensitivity for Identifying Recurrent/Persistent Disease in Patients With Low‐risk Thyroid Cancer Treated With Total Thyroidectomy and Radioactive Iodine Ablation, Making Stimulated Thyroglobulin Unnecessary

Domínguez

Nilo

Contreras

et al. 2017

J of Ultrasound Medicine

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Papillary thyroid microcarcinoma: characteristics at presentation, and evaluation of clinical and histological features associated with a worse prognosis in a Latin American cohort

Domínguez¹,

Nilo²,

Martínez³

et al. 2018

Archives of Endocrinology and Metabolism

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Objective We aimed to describe the presentation of papillary microcarcinoma (PTMC) and identify the clinical and histological features associated with persistence/recurrence in a Latin American cohort. Subjects and methods Retrospective study of PTMC patients who underwent total thyroidectomy, with or without radioactive iodine (RAI), and who were followed for at least 2 years. Risk of recurrence was estimated with ATA 2009 and 2015 classifications, and risk of mortality with 7th and 8th AJCC/TNM systems. Clinical data obtained during follow-up were used to detect structural and biochemical persistence/recurrence. Results We included 209 patients, predominantly female (90%), 44.5 ± 12.6 years old, 183 (88%) received RAI (90.4 ± 44.2 mCi), followed-up for a median of 4.4 years (range 2.0-7.8). The 7th and 8th AJCC/TNM system classified 89% and 95.2% of the patients as stage I, respectively. ATA 2009 and ATA 2015 classified 70.8% and 78.5% of the patients as low risk, respectively. Fifteen (7%) patients had persistence/recurrence during follow-up. In multivariate analysis, only lymph node metastasis was associated with persistence/recurrence (coefficient beta 4.0, p = 0.016; 95% CI 1.3-12.9). There were no PTMC related deaths. Conclusions Our series found no mortality and low rate of persistence/recurrence associated with PTMC. Lymph node metastasis was the only feature associated with recurrence in multivariate analysis. The updated ATA 2015 and 8th AJCC/TNM systems classified more PTMCs than previous classifications as low risk of recurrence and mortality, respectively.

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Del macro al microcarcinoma tiroideo: cambios en las características de presentación del cáncer de tiroides en un centro universitario chileno en 20 años

Abstract: (Rev Med Chile 2013; 141: 442-448).

Cited by 4 publications

References 13 publications

Microcalcificaciones y focos ecogénicos puntiformes, ¿qué tan bien sabemos lo que estamos viendo?

Microcalcificaciones y focos ecogénicos puntiformes, ¿qué tan bien sabemos lo que estamos viendo?

Neck Sonography and Suppressed Thyroglobulin Have High Sensitivity for Identifying Recurrent/Persistent Disease in Patients With Low‐risk Thyroid Cancer Treated With Total Thyroidectomy and Radioactive Iodine Ablation, Making Stimulated Thyroglobulin Unnecessary

Papillary thyroid microcarcinoma: characteristics at presentation, and evaluation of clinical and histological features associated with a worse prognosis in a Latin American cohort

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