This paper presents asymptotic stability criteria for fractional‐order gene regulatory networks (FOGRNs) with impulses, time delays, and two numerical cases to illustrate the applicability of the results. The established system's boundedness, existence, and uniqueness are discussed using the Mittag–Leffler function, homeomorphism theory, and Cauchy–Schwartz inequality. The delay‐independent asymptotic stability criteria for FOGRNs are derived using algebraic and LMI methods, famous inequality techniques, and Lyapunov stability theory.