“…For unconstrained systems, one can consider ordinary delay differential equations with an addition to the dynamics in the form of white noise or even a state dependent noise. There is a sizeable literature on such stochastic delay differential equations (SDDE) especially when the associated noiseless system has a globally attracting equilibrium [2,7,11,15,19,20,22,23,30,34,35,36]. To obtain the analogue of such SDDE models with non-negativity constraints, it is not simply a matter of adding a noise term to the ordinary differential equation dynamics, as this will typically not lead to a solution respecting the state constraint (even if the deterministic model was naturally constrained).…”