Objectives The aim of this study was to determine the length of delays and to investigate the factors associated with patient (care-seeking) and health-system (treatment initiation following care-seeking) delays, among smearpositive tuberculosis patients in Kunar province, Afghanistan, as delay in diagnosis and treatment results in more severe disease, higher mortality, and a longer period of infectivity in the community. Methods A cross-sectional study of 122 new smearpositive pulmonary tuberculosis patients, aged C15 years, registered at a hospital and a clinic in Kunar province, was conducted from