Delayed development of enhancement in fat necrosis after breast conservation therapy: a potential pitfall of MR imaging of the breast.

Solomon, Brian A.; Orel, Susan G.; Reynolds, Carol; Schnall, Mitchell D.

doi:10.2214/ajr.170.4.9530045

Cited by 54 publications

(18 citation statements)

References 6 publications

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“…Mammography, though still the criterion standard, 53,63 may result in false-positives (18 percent). 64,65 Mammography detects only two-thirds of recurrences, and in approximately 45 percent of cases, the recurrences (in situ or invasive) occur as microcalcifications.…”

Section: Discussionmentioning

confidence: 99%

“…64,65 Mammography detects only two-thirds of recurrences, and in approximately 45 percent of cases, the recurrences (in situ or invasive) occur as microcalcifications. 63 Mammography is the only examination that can clearly identify microcalcifications and distinguish them from those that are malignant. 5 In addition, mammography allows us to identify the typical soap bubble, macrocalcifications, and breast opacity.…”

Section: Discussionmentioning

confidence: 99%

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Magnetic Resonance Imaging and Ultrasound Evaluation after Breast Autologous Fat Grafting Combined with Platelet-Rich Plasma

Fiaschetti

Pistolese

Fornari

et al. 2013

Plastic and Reconstructive Surgery

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Magnetic Resonance Imaging and Ultrasound Evaluation after Breast Autologous Fat Grafting Combined with Platelet-Rich Plasma

Fiaschetti

Pistolese

Fornari

et al. 2013

Plastic and Reconstructive Surgery

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“…Reported sensitivities have ranged from 93% to 100%, with reported specificities ranging from 88% to 100% (78 -87). False-positive cases have included inflammatory changes and fat necrosis ( Fig 6) (88). The differentiation of enhancing recurrent cancer from enhancing posttreatment changes can be difficult in the early posttreatment period.…”

Section: Problem Solving: Is Cancer Present?mentioning

confidence: 99%

“…The differentiation of enhancing recurrent cancer from enhancing posttreatment changes can be difficult in the early posttreatment period. Investigators thus far have reported that enhancement secondary to radiation-induced changes can be present for at least 18 months after treatment (88,89). On the basis of the promising results of clinical investigation thus far, it appears that MR imaging will play a role in the evaluation of patients following breast conservation.…”

Section: Problem Solving: Is Cancer Present?mentioning

confidence: 99%

MR Imaging of the Breast for the Detection, Diagnosis, and Staging of Breast Cancer

Orel

Schnall²

2001

Radiology

691

422

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With the introduction of contrast agents, advances in surface coil technology, and development of new imaging protocols, contrast agent-enhanced magnetic resonance (MR) imaging has emerged as a promising modality for detection, diagnosis, and staging of breast cancer. The reported sensitivity of MR imaging for the visualization of invasive cancer has approached 100%. There are many examples in the literature of MR imaging--demonstrated mammographically, sonographically, and clinically occult breast cancer. Often, breast cancer detected on MR images has resulted in a change in patient care. Despite these results, there are many unresolved issues, including no defined standard technique for contrast-enhanced breast MR imaging, no standard interpretation criteria for evaluating such studies, no consensus on what constitutes clinically important enhancement, and no clearly defined clinical indications for the use of MR imaging. Furthermore, this technology remains costly, and issues of cost-effectiveness and cost competition from percutaneous biopsy have yet to be fully addressed. These factors along with the lack of commercially available MR imaging--guided localization and biopsy systems have slowed the transfer of this imaging technology from research centers to clinical breast imaging practices. Technical requirements, potential clinical applications, and potential pitfalls and limitations of contrast-enhanced MR imaging as a method to help detect, diagnose, and stage breast cancer will be described.

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“…DCE-MRI is useful for determining the biological properties of a tumor because contrast enhancement features are representative of histologic features of the tumor [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Optimal Clustering of Kinetic Patterns on Malignant Breast Lesions: Comparison between K-means Clustering and Three-time-points Method in Dynamic Contrast-enhanced MRI

Lee

Kim

et al. 2007

2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is useful for breast cancer diagnosis and treatment planning. Nevertheless, due to the multi-temporal nature of DCE-MRI data, the assessment of early stage breast cancer is a challenging task. In this study, we applied an unsupervised clustering approach and cluster validation technique to the analysis of malignant intral-tumoral kinetic curves in DCE-MRI. K-means cluster analysis was performed from real world malignant tumor cases and the data were transformed into an optimal number of reference patterns representative each cluster. The optimal number of clusters was estimated by a cluster validation index, which was calculated with the ratio of inter-class scatter to intra-class scatter. This technique then classifies tumor specific patterns from a given MRI data by measuring the vector distances from the reference pattern set, and compared the result from the k-means clustering with that from three-time-points (3TP) method, which represents a clinical standard protocol for analysis of tumor kinetics. The evaluation of twenty five cases indicates that optimal k-means clustering reflects partitioning intra-tumoral kinetic patterns better than the 3TP technique. This method will greatly enhance the capability of radiologists to identify and characterize internal kinetic heterogeneity and vascular change of a tumor in breast DCE-MRI.

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Delayed development of enhancement in fat necrosis after breast conservation therapy: a potential pitfall of MR imaging of the breast.

Cited by 54 publications

References 6 publications

Magnetic Resonance Imaging and Ultrasound Evaluation after Breast Autologous Fat Grafting Combined with Platelet-Rich Plasma

Magnetic Resonance Imaging and Ultrasound Evaluation after Breast Autologous Fat Grafting Combined with Platelet-Rich Plasma

MR Imaging of the Breast for the Detection, Diagnosis, and Staging of Breast Cancer

Optimal Clustering of Kinetic Patterns on Malignant Breast Lesions: Comparison between K-means Clustering and Three-time-points Method in Dynamic Contrast-enhanced MRI

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