2020
DOI: 10.1016/j.oooo.2020.06.006
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Delayed diagnosis and inappropriate clinical management of nicorandil-induced oral lesions: A case report

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Cited by 2 publications
(3 citation statements)
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“…Nicorandil is a coronary vasodilator and is commonly used in coronary heart disease (Babic et al, 2018). Nicorandil‐induced ulcer (NIU) is not a well‐recognized adverse effect, with a delayed diagnosis and inadequate management (Babic et al, 2018; Takadoum et al, 2020). The pathogenesis is largely unknown.…”
Section: Diagnosismentioning
confidence: 99%
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“…Nicorandil is a coronary vasodilator and is commonly used in coronary heart disease (Babic et al, 2018). Nicorandil‐induced ulcer (NIU) is not a well‐recognized adverse effect, with a delayed diagnosis and inadequate management (Babic et al, 2018; Takadoum et al, 2020). The pathogenesis is largely unknown.…”
Section: Diagnosismentioning
confidence: 99%
“…NIU develops 0.2–5% in patients treated with nicorandil (Babic et al, 2018). The onset of nicorandil‐induced ulcer is generally within 2 years after the start of nicorandil although some cases occur after several years (Babic et al, 2018; Takadoum et al, 2020). Severe cases are frequent when the dose exceeds the maximum recommendation (40 mg/day).…”
Section: Diagnosismentioning
confidence: 99%
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