2013
DOI: 10.1590/s1806-37132013000500003
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Delayed diagnosis of sarcoidosis is common in Brazil

Abstract: Objective: To determine the frequency of and the factors related to delayed diagnosis of sarcoidosis in Brazil. Methods: We evaluated patients with a biopsy-proven diagnosis of sarcoidosis, using a questionnaire that addressed the following: time since symptom onset and since the first medical visit; and the number and specialty of the physicians visited. We divided the patients by the timeliness of the diagnosis-timely (< 6 months) and delayed (≥ 6 months)-comparing the two groups in terms of systemic and pul… Show more

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Cited by 15 publications
(12 citation statements)
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“…A study from Brazil evaluated 100 patients with a biopsy-proven diagnosis of sarcoidosis. The median number of physicians consulted was 3 (range, 1–14), and the diagnosis of sarcoidosis was timely in 41 patients and delayed in 59 [ 6 ]. The typical radiologic findings associated with sarcoidosis include symmetric, bilateral hilar, and paratracheal lymphadenopathy, with or without concomitant parenchymal abnormalities.…”
Section: Case Presentationmentioning
confidence: 99%
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“…A study from Brazil evaluated 100 patients with a biopsy-proven diagnosis of sarcoidosis. The median number of physicians consulted was 3 (range, 1–14), and the diagnosis of sarcoidosis was timely in 41 patients and delayed in 59 [ 6 ]. The typical radiologic findings associated with sarcoidosis include symmetric, bilateral hilar, and paratracheal lymphadenopathy, with or without concomitant parenchymal abnormalities.…”
Section: Case Presentationmentioning
confidence: 99%
“…The pathological diagnosis of sarcoidosis was determined after a video-assisted thoracoscopic procedure. Timely and correct diagnosis is very important for improving pulmonary function and determining the presence of lesions in other organs, while delayed diagnosis is often associated with an impaired lung function and medication induced impairment of the other organs [ 6 ]. For example, many sarcoidosis patients are misdiagnosed with tuberculosis and treated with anti-tuberculosis drugs who eventually developed with liver function impairment.…”
Section: Case Presentationmentioning
confidence: 99%
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“…Furthermore, since sarcoidosis is a diagnosis of exclusion, the physician should always maintain a healthy degree of skepticism concerning the diagnosis [ 3 ]. On the other hand, due to lack of specificity of granulomatous diseases and the continued high prevalence of tuberculosis in our country, many sarcoidosis patients are misdiagnosed with tuberculosis and treated for the condition [ 23 ].…”
Section: Discussionmentioning
confidence: 99%
“…A delayed diagnosis was seen in other series, but this is probably more common in less developed countries, since it could depend on medical and socioeconomic aspects, and sarcoidosis may be misdiagnosed as TB. 27,49,[68][69][70] Researchers from the recent GenPhenReSa project stratified patients into five distinct phenotype subgroups according to predominant organ involvement: (1) abdominal organ involvement, (2) ocular-cardiac-cutaneous-central nervous system involvement, (3) musculoskeletal-cutaneous involvement, (4) pulmonary and intrathoracic lymph node involvement, and (5) extrapulmonary involvement. The major phenotype associated with an acute onset is subgroup 3: higher frequencies of fever or subfebrile temperature, night sweats, weight loss, and arthralgia; lower frequencies of lung or bronchial disease; and more frequent involvement of the skin, intrathoracic lymph nodes, and kidneys.…”
Section: Organ Involvementmentioning
confidence: 99%