Abstract:Disseminated intravascular coagulopathy (DIC) is a very rare outcome post endovascular repair of aortic aneurysm dissections. We present a case of a 70-year-old male who presented with DIC post a thoracic endovascular aortic repair (TEVAR) procedure due to a type 1A endoleak. Initially, the patient was treated with red blood cells and blood products; however, when failing to improve, he underwent a hybrid arch replacement. In this study, we will analyze the management of DIC post TEVAR and look at its presenta… Show more
“…7-9 The first case of DIC after TEVAR was reported in 2014 in a small case series of Nienaber et al 6 Another 9 cases were reported until 2020. 10-19 In Table 3, patients’ age and gender, comorbidities, primary disease, initial intervention, and DIC time of diagnosis and clinical manifestations are reported.Figure 3.Flow diagram depicting the selection process of the cases included in the review.…”
Section: Resultsmentioning
confidence: 99%
“…In 2000, Cross et al described the first case of a female presenting with DIC following EVAR, 1 and another 16 cases have been published ever since. [6][7][8][9][10][11][12][13][14][15][16][17][18][19] In the absence of robust data and pertinent guidelines, high uncertainty is present in the management of DIC post-EVAR. This review aimed to summarize the existing evidence, assist the decision-making process in clinical practice, and form a basis for further relevant research.…”
Background Disseminated Intravascular Coagulation (DIC) after Endo-Vascular Aneurysm Repair (EVAR) is a highly uncommon clinical entity. With only a few case-reports available, its management strategy still remains enigmatic. Objectives The purpose of this study was to retrieve, synthesize, and appraise all existing data for DIC after EVAR. Materials and methods All published articles regarding DIC post-EVAR were identified from 3 major databases and analyzed. Clinical parameters, predisposing factors, along with mortality and morbidly were assessed. Results The total number of publications included in the review was 15 describing 17 cases. DIC presented with a broad spectrum of clinical manifestations, while the time of diagnosis varied significantly. Endoleak was the main causative factor, with an incidence reaching 71%. The mortality of DIC after EVAR reached 29%, regardless of the therapeutic approach chosen. DIC was treated effectively in 47% of the patients (8/17), with better outcomes among patients who received conservative therapy or among those who were submitted to endovascular interventions. Conclusions DIC after EVAR, although rare, is a potentially lethal clinical condition which requires prompt diagnosis and urgent medical consideration. Treatment of endoleak may help in quick restoration of normal parameters
“…7-9 The first case of DIC after TEVAR was reported in 2014 in a small case series of Nienaber et al 6 Another 9 cases were reported until 2020. 10-19 In Table 3, patients’ age and gender, comorbidities, primary disease, initial intervention, and DIC time of diagnosis and clinical manifestations are reported.Figure 3.Flow diagram depicting the selection process of the cases included in the review.…”
Section: Resultsmentioning
confidence: 99%
“…In 2000, Cross et al described the first case of a female presenting with DIC following EVAR, 1 and another 16 cases have been published ever since. [6][7][8][9][10][11][12][13][14][15][16][17][18][19] In the absence of robust data and pertinent guidelines, high uncertainty is present in the management of DIC post-EVAR. This review aimed to summarize the existing evidence, assist the decision-making process in clinical practice, and form a basis for further relevant research.…”
Background Disseminated Intravascular Coagulation (DIC) after Endo-Vascular Aneurysm Repair (EVAR) is a highly uncommon clinical entity. With only a few case-reports available, its management strategy still remains enigmatic. Objectives The purpose of this study was to retrieve, synthesize, and appraise all existing data for DIC after EVAR. Materials and methods All published articles regarding DIC post-EVAR were identified from 3 major databases and analyzed. Clinical parameters, predisposing factors, along with mortality and morbidly were assessed. Results The total number of publications included in the review was 15 describing 17 cases. DIC presented with a broad spectrum of clinical manifestations, while the time of diagnosis varied significantly. Endoleak was the main causative factor, with an incidence reaching 71%. The mortality of DIC after EVAR reached 29%, regardless of the therapeutic approach chosen. DIC was treated effectively in 47% of the patients (8/17), with better outcomes among patients who received conservative therapy or among those who were submitted to endovascular interventions. Conclusions DIC after EVAR, although rare, is a potentially lethal clinical condition which requires prompt diagnosis and urgent medical consideration. Treatment of endoleak may help in quick restoration of normal parameters
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