Delayed Enhancement Magnetic Resonance Imaging in Nonischemic Myocardial Disease

Moraes, Gustavo L.; Higgins, Charles B.; Ordovás, Karen

doi:10.1097/rti.0b013e3182828f89

Cited by 17 publications

(9 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Global involvement of myocardial inflammation in CS may also occur. However, atrial thickening and atrial LGE are more commonly observed in amyloidosis and may help differentiate this condition from CS (83). Definitive involvement by amyloidosis is established histologically on the basis of the presence of apple-green birefringence at polarizing light microscopy (Fig 20).…”

Section: Amyloidosismentioning

confidence: 99%

Cardiac Sarcoidosis: The Challenge of Radiologic-Pathologic Correlation:From the Radiologic Pathology Archives

Jeudy¹,

Burke²,

White³

et al. 2015

RadioGraphics

View full text Add to dashboard Cite

Cardiac sarcoidosis is a rare but potentially fatal disorder with a nonspecific spectrum of clinical manifestations, including conduction disorders, congestive heart failure, ventricular arrhythmias, and sudden cardiac death. Although early treatment to improve morbidity and mortality is desirable, sensitive and accurate detection of cardiac sarcoidosis remains a challenge. Except for the histopathologic finding of noncaseating granulomas in an endomyocardial biopsy specimen, most diagnostic tests are limited and nonspecific at best. Therefore, the decision to initiate treatment is based largely on the patient's clinical symptoms and the course of the disease, rather than histologic confirmation. Successful recognition of cardiac sarcoidosis ultimately requires rigorous collaboration among a clinician, radiologist, and pathologist. Advanced imaging modalities, such as cardiac magnetic resonance imaging and positron emission tomography with fluorodeoxyglucose, have become increasingly useful in facilitating diagnosis and therapeutic monitoring, although limited prospective studies exist. This article describes the clinical parameters and pathologic findings of cardiac sarcoidosis and the advanced imaging features and differential diagnostic challenges that must be considered for a successful diagnostic approach. In addition, to improve the understanding of abnormalities detected with different imaging modalities, we suggest a unified terminology in describing radiologic findings related to cardiac sarcoidosis.

show abstract

Section: Amyloidosismentioning

confidence: 99%

Cardiac Sarcoidosis: The Challenge of Radiologic-Pathologic Correlation:From the Radiologic Pathology Archives

Jeudy¹,

Burke²,

White³

et al. 2015

RadioGraphics

View full text Add to dashboard Cite

show abstract

“…Approximately 7-8 minutes after contrast material injection, a variable-inversiontime scout sequence is performed to select the inversion time that nulls the normal myocardial signal (a typical inversion time is 200-300 msec). Imaging acquisition 10-15 minutes after injection is performed with a short-axis myocardial signal-nulled T1-weighted sequence from the base toward the apex (44). Of note, superior contrast between normal and abnormal myocardium on contrast material-enhanced images has been shown 5-8 minutes after gadolinium administration instead of the imaging delay of 10-15 minutes generally used in contrast-enhanced cardiac MR imaging.…”

Section: Technical Considerations In Cardiac Mr Imagingmentioning

confidence: 99%

Amyloidosis: Modern Cross-sectional Imaging

et al. 2015

View full text Add to dashboard Cite

Amyloidosis is a rare diverse condition caused by the pathologic extracellular deposition of abnormal insoluble proteins throughout the body. It may exist as a primary disease or, more commonly, may be secondary to a wide variety of pathologic processes ranging from chronic infection or inflammation to malignancy. Hereditary forms also exist. On the basis of the structure of the protein deposits, more than two dozen subtypes of amyloidosis have been described. A single organ or multiple organ systems may be affected. The radiologic manifestations of amyloidosis are varied and often nonspecific, making amyloidosis a diagnostic challenge for the radiologist. In the chest, the lungs, mediastinum, pleura, and heart may be involved. Lung involvement may manifest as diffuse reticulonodular interstitial thickening, consolidations, or solitary or multiple parenchymal nodules that may calcify, cavitate, and slowly enlarge. Pleural involvement most commonly manifests as pleural effusions. Tracheobronchial involvement may exhibit concentric airway thickening, mural and intraluminal nodules, submucosal calcification, and airway obstruction. Mediastinal and hilar lymph nodes may enlarge and frequently calcify. At cardiac magnetic resonance (MR) imaging, the left ventricular wall is typically thickened, with associated diastolic dysfunction. Delayed contrast material-enhanced cardiac MR imaging typically shows global transmural or subendocardial enhancement. The pathophysiology, classification, treatment, and prognosis of amyloidosis are reviewed, followed by case examples of the appearance of thoracic and cardiac amyloidosis on chest radiographs, computed tomographic (CT) images, and cardiac MR images.

show abstract

“…Although catheter ablation reduces recurrences of sustained MMVT in patients with ischaemic cardiomyopathy, a reduction in mortality has yet to be demonstrated [150]. Catheter ablation has also been successfully used in patients with non-ischaemic cardiomyopathy where the ablation target is often on the epicardial surface of the ventricles and the procedure may be more complex [151][152][153][154][155][156]. The long-term effectiveness of catheter ablation for non-ischaemic cardiomyopathies has been less well studied than for ischaemic cardiomyopathies.…”

Section: Catheter Ablationmentioning

confidence: 99%