Mesh erosion is a phenomenon whereby soft tissue becomes damaged as a result of contact with implants made from surgical mesh, a fabric-like material consisting of fibers of polypropylene or other polymers. This paper describes the design and construction of a testing machine to generate mesh erosion in vitro. A sample of mesh in the form of a 10 mm wide tape is pressed against soft tissue (porcine muscle) with a given force, and a given reciprocating movement is applied between the mesh and the tissue. To demonstrate the capabilities of the equipment, we measured erosion using the same mesh and tissue type, varying the applied force and the reciprocating stroke length, including zero strokes (i.e., static loading). For comparison, we also tested four other samples of polypropylene with different edge characteristics. Analysis of the results suggests the existence of three different erosion mechanisms: cutting, wear and creep. It is concluded that the equipment provides a useful and realistic simulation of mesh erosion, a phenomenon that is of great clinical significance and merits further study.