Abstract:Mitochondrial dysfunction is shown to be associated with many diseases, such as neurodegeneration, diabetes, cardiomyopathy or developmental delay, etc. Energy generation in the mitochondria meets the demands and is extremely specific to different tissues. The brain is rather small (1-2% of body weight) in relation to the whole body, but it consumes ten times more oxygen and glucose than any other tissue. Oxygen is consumed predominantly in the mitochondria, in the electron transport chain (ETC) in a process t… Show more
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