Delayed postanoxic encephalopathy after carbon monoxide poisoning

Kwon, O‐Yu; Chung, Sung Phil; Ha, Young Rock; Yoo, In Sool; Kim, Seung Whan

doi:10.1136/emj.2002.002014

Cited by 54 publications

(34 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The patients described in three of the prior studies and the patients in our sample were over 30 years of age [7,8,16], whereas the patient described by Wallace et al was 28 years of age [9]. Choi, Kim, and Kwon also describe patients over the age of 30 years with delayed neurologic sequelae secondary to carbon monoxide intoxication [10,11,17]. Similar to prior studies, the patients described in this study showed a return to near neurological baseline within 6 to 12 months after the initial event.…”

Section: Discussionmentioning

confidence: 88%

Reversible delayed posthypoxic leukoencephalopathy after drug overdose: MRI findings in a collection of patients

2012

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 88%

Reversible delayed posthypoxic leukoencephalopathy after drug overdose: MRI findings in a collection of patients

2012

View full text Add to dashboard Cite

“…With continued anaerobic metabolism, cellular death occurs, continuing a vicious cycle that ultimately progresses to organ failure if not reversed. 9 CO also binds with cardiac myoglobin, causing hypoxia in cardiac tissue that may lead to cardiac ischemia. 4 Research indicates that 37% of patients with moderate-to-severe CO toxicity develop ECG abnormalities and/or elevation of serum cardiac biomarkers.…”

Section: Cellular Damage: An Inside Jobmentioning

confidence: 99%

Acute carbon monoxide toxicity

Laing¹

2013

Nursing Critical Care

View full text Add to dashboard Cite

“…It is worth mentioning that many patients with severe CO poisoning develop delayed encephalopathy and cognitive sequelae even after 4 weeks of conventional hyperbaric oxygen therapy. 10 Our patient was followed for ϳ6 months and never reported clinical symptoms of encephalopathy.…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Severe Carbon Monoxide Poisoning and Refractory Shock Using Extracorporeal Membrane Oxygenation

et al. 2015

View full text Add to dashboard Cite

Carbon monoxide (CO) is the most common cause of poisoning and poisoning-related death in the United States. It is a tasteless and odorless poisonous gas produced from incomplete combustion of hydrocarbons, such as those produced by cars and heating systems. CO rapidly binds to hemoglobin to form carboxyhemoglobin, leading to tissue hypoxia, multiple-organ failure, and cardiovascular collapse. CO also binds to myocardial myoglobin, preventing oxidative phosphorylation in cardiac mitochondria and resulting in cardiac ischemia or stunning and cardiogenic pulmonary edema. Treatment of CO poisoning is mainly supportive, and supplemental oxygen remains the cornerstone of therapy, whereas hyperbaric oxygen therapy is considered for patients with evidence of neurological and myocardial injury. Extracorporeal membrane oxygenation (ECMO) has been utilized effectively in patients with respiratory failure and hemodynamic instability, but its use has rarely been reported in patients with CO poisoning. We report the successful use of venoarterial ECMO in a patient with severe CO poisoning and multiple-organ failure.

show abstract

Delayed postanoxic encephalopathy after carbon monoxide poisoning

Cited by 54 publications

References 10 publications

Reversible delayed posthypoxic leukoencephalopathy after drug overdose: MRI findings in a collection of patients

Reversible delayed posthypoxic leukoencephalopathy after drug overdose: MRI findings in a collection of patients

Acute carbon monoxide toxicity

Successful Treatment of Severe Carbon Monoxide Poisoning and Refractory Shock Using Extracorporeal Membrane Oxygenation

Contact Info

Product

Resources

About