Delayed Reconstruction of Palatomaxillary Defect Using Fibula Free Flap

Byun, Soo-Hwan; Lim, Ho-Kyung; Yang, Byoung-Eun; Kim, Soung Min; Lee, Jong Ho

doi:10.3390/jcm9030884

Cited by 12 publications

(18 citation statements)

References 43 publications

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“…The use of bone grafts on bony defects caused by tumors, trauma, or aging is an established and standardized procedure which has been clinically successful over a long period of time [ 1 , 2 , 3 ]. Many reports have been published on successful bone healing after autogenous, allogeneic, xenogeneic, and alloplastic bone grafting [ 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

3D-Printed Ceramic Bone Scaffolds with Variable Pore Architectures

Lim

Hong

Byeon

et al. 2020

IJMS

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This study evaluated the mechanical properties and bone regeneration ability of 3D-printed pure hydroxyapatite (HA)/tricalcium phosphate (TCP) pure ceramic scaffolds with variable pore architectures. A digital light processing (DLP) 3D printer was used to construct block-type scaffolds containing only HA and TCP after the polymer binder was completely removed by heat treatment. The compressive strength and porosity of the blocks with various structures were measured; scaffolds with different pore sizes were implanted in rabbit calvarial models. The animals were observed for eight weeks, and six animals were euthanized in the fourth and eighth weeks. Then, the specimens were evaluated using radiological and histological analyses. Larger scaffold pore sizes resulted in enhanced bone formation after four weeks (p < 0.05). However, in the eighth week, a correlation between pore size and bone formation was not observed (p > 0.05). The findings showed that various pore architectures of HA/TCP scaffolds can be achieved using DLP 3D printing, which can be a valuable tool for optimizing bone-scaffold properties for specific clinical treatments. As the pore size only influenced bone regeneration in the initial stage, further studies are required for pore-size optimization to balance the initial bone regeneration and mechanical strength of the scaffold.

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Section: Introductionmentioning

confidence: 99%

3D-Printed Ceramic Bone Scaffolds with Variable Pore Architectures

Lim

Hong

Byeon

et al. 2020

IJMS

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“…FFF can be harvested with an expendable long and rigid bone [15]. Byun et al reported nine cases of successful secondary palatomaxillary reconstructions using FFF, which indicates that the length of the vascular pedicle in FFF is su cient to reach the vessels on the contralateral side [16]. Thus, none of the four cases of secondary mandibular reconstructions performed at our institution required vein grafting, and all of them resulted in ap survival.…”

Section: Discussionmentioning

confidence: 80%

Safety and Efficacy of Secondary Mandibular Reconstruction Using a Free Osteo-cutaneous Fibula Flap after Segmental Mandibular Resection: A Retrospective Case Control Study

Yamakawa

Hayashida

2021

Preprint

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Background: Free osteocutaneous fibula flap (FFF) is currently considered the best option for segmental mandibular reconstruction; however, there are no reports comparing secondary with primary reconstructions using FFF. This study aimed to evaluate the safety and efficacy of secondary mandibular reconstruction using FFF when compared with primary mandibular reconstruction. Methods: From October 2018 to February 2020, patients who underwent mandibular reconstruction using FFF after segmental mandibulectomy were retrospectively reviewed. The size and location of the mandibular defect, the segment length and number of osteotomies in the fibula, types of the mandibular plating system, and laterality of the recipient vessels were recorded from the surgical notes. Flap survival, duration of nasogastric tube use, and implant installation after reconstruction were recorded as indices of postoperative evaluation. Results: Twelve patients underwent mandibular reconstruction using FFF during the study period. There were no significant differences in demographic characteristics other than body mass index between the primary (n=8) and secondary (n=4) reconstruction groups. No significant differences were observed in the size and location of defects, the segment length and number of osteotomies in the fibula, and the types of mandibular plating system. The laterality of recipient vessels was ipsilateral in all cases of primary reconstructions and contralateral in all cases of secondary reconstructions. Three out of eight patients with primary FFF reconstruction developed partial flap necrosis. Four patients in the secondary FFF reconstruction group achieved complete flap survival. The duration of use of the nasogastric tube and implant installation after reconstruction was comparable between the two groups. Conclusion: This clinical case study demonstrates the safety and efficacy of secondary mandibular reconstructions using FFF.

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“…The fibula was first utilized by Hidalgo et al ( 64 ) for mandibular reconstruction in 1989. Compared with other options, the fibula has gained widespread use, owing to its versatility by offering great length and thickness of bone, intraosseous and segmental blood supply, and reliable skin paddle for simultaneous soft tissue reconstruction ( 65 , 66 ). Therefore, the use of the fibula for mandibular reconstruction is well accepted among numerous oral maxillofacial surgeons ( 62 ).…”

Section: Discussionmentioning

confidence: 99%