Delays in presentation of intussusception and development of gangrene in Zimbabwe

Burnett, Eleanor; Mujuru, Hilda; Nathoo, Kusum; Tate, Jacqueline E.; Mwenda, Jason M.; Weldegebriel, Goitom; Manangazira, Portia; Mukaratirwa, Arnold; Parashar, Umesh D.; Zimunhu, Taurai; Mbuwayesango, Bothwell

doi:10.11604/pamj.supp.2021.39.1.21301

Cited by 4 publications

(7 citation statements)

References 49 publications

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“…This finding is opposed to some other publications where bowel resection featured less prominently 9,21,26 . The high prominence of bowel resection as a treatment modality is likely due to persisting late presentation as also seen in many other African studies 11,14,20,22,23 . Bowel resection was also the main treatment modality in some other publications 1,13,14,19,20,29 .…”

Section: Discussionmentioning

confidence: 78%

Trends in childhood intussusception in a Nigerian tertiary hospital

Obiora Ezomike,

Ifeanyi Nwangwu,

Sunday Chukwu

et al. 2024

Afr H. Sci.

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Background: Early presentation, high rate of successful non-operative treatment, low morbidity and mortality in childhood intussusception is common in High and Upper Middle-Income Countries but not in many Lower middle- and Low-income countries. Aim: To assess the trends in the profile, treatment modalities and outcomes of intussusception in our hospital. Materials and methods: Retrospective study over a 12-year period divided into two 6-year periods. Data entry/analysis was done using SPSS and various indices were compared between these two periods. Two-tailed t-test for two independent means was used to compare means while two-tailed Fisher exact tests were used to compare categorical variables. Results were presented as tables, means, ranges, percentages and a p-value less than 0.05 was deemed statistically significant. Results: There was a significant increase in the proportion of successful non-operative treatment (18.6% vs 34%, p=0.03), reduction in the incidence of operative manual reduction (27.1% vs 12.8%; p=0.026), reduction in operative treatment (78.5% vs 63.9%, p=0.034), increased utilization of pre-intervention ultrasound (75% vs96.7%, p<0.0001) and reduction in hospital stay duration (10.47 ±7.95days vs 7.24±4.86 days; p=0.004). Conclusions: Contribution of successful non-operative treatment to the overall treatment of intussusception significantly increased while that of operative manual reduction significantly reduced and bowel resection showed no change. Preoperative utilization of ultrasonography significantly increased while mean duration of admission reduced significantly, but late presentation, morbidity and mortality rates had no significant changes. Keywords: Trends; childhood; intussusception; Nigerian; tertiary hospital.

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Section: Discussionmentioning

confidence: 78%

Trends in childhood intussusception in a Nigerian tertiary hospital

Obiora Ezomike,

Ifeanyi Nwangwu,

Sunday Chukwu

et al. 2024

Afr H. Sci.

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“…This was anticipated given the variability in resources and transportation options between sites. Few studies have been designed to allow cross-country comparisons of delays in healthcare seeking [ 8 , 11 , 23 ]. Caregivers at each site shared similar patterns in healthcare seeking delays in the home, which points toward widespread need for improved education on when to seek clinical care for infants and children.…”

Section: Discussionmentioning

confidence: 99%

Identifying delays in healthcare seeking and provision: The Three Delays-in-Healthcare and mortality among infants and children aged 1–59 months

Garcia Gomez,

Igunza,

Madewell

et al. 2024

PLOS Glob Public Health

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Delays in illness recognition, healthcare seeking, and in the provision of appropriate clinical care are common in resource-limited settings. Our objective was to determine the frequency of delays in the “Three Delays-in-Healthcare”, and factors associated with delays, among deceased infants and children in seven countries with high childhood mortality. We conducted a retrospective, descriptive study using data from verbal autopsies and medical records for infants and children aged 1–59 months who died between December 2016 and February 2022 in six sites in sub-Saharan Africa and one in South Asia (Bangladesh) and were enrolled in Child Health and Mortality Prevention Surveillance (CHAMPS). Delays in 1) illness recognition in the home/decision to seek care, 2) transportation to healthcare facilities, and 3) the receipt of clinical care in healthcare facilities were categorized according to the “Three Delays-in-Healthcare”. Comparisons in factors associated with delays were made using Chi-square testing. Information was available for 1,326 deaths among infants and under 5 children. The majority had at least one identified delay (n = 854, 64%). Waiting >72 hours after illness recognition to seek health care (n = 422, 32%) was the most common delay. Challenges in obtaining transportation occurred infrequently when seeking care (n = 51, 4%). In healthcare facilities, prescribed medications were sometimes unavailable (n = 102, 8%). Deceased children aged 12–59 months experienced more delay than infants aged 1–11 months (68% vs. 61%, P = 0.018). Delays in seeking clinical care were common among deceased infants and children. Additional study to assess the frequency of delays in seeking clinical care and its provision among children who survive is warranted.

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“…As an exploratory analysis, we considered the relationship between delayed presentation and gangrene. 25,26…”

Section: Discussionmentioning

confidence: 99%

Prevalence, Surgical Management, and Outcome of Intussusception in Children : A Comprehensive Systematic Review

Aisyah Sabrina,

Jalaluddin Machalli,

Nuraziza

et al. 2024

JARMHS

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Background: Intussusception is the invagination of a segment of bowel into an adjacent segment resulting into an intestinal obstruction. It is the most common acquired cause of intestinal obstruction in children under the age of 2 years. The aim: The aim of this study to show about prevalence, surgical management, and outcome of intussusception in children. Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. Result: Ten publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: Nonoperative management of intussusception should be adopted in carefully selected cases of intussusception in this subregion as it will help to reduce the financial burden on the parents while surgical management should be reserved for the complicated cases.

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Delays in presentation of intussusception and development of gangrene in Zimbabwe

Cited by 4 publications

References 49 publications

Trends in childhood intussusception in a Nigerian tertiary hospital

Trends in childhood intussusception in a Nigerian tertiary hospital

Identifying delays in healthcare seeking and provision: The Three Delays-in-Healthcare and mortality among infants and children aged 1–59 months

Prevalence, Surgical Management, and Outcome of Intussusception in Children : A Comprehensive Systematic Review

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