2024
DOI: 10.1001/jamanetworkopen.2024.13955
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Delays to Antibiotics in the Emergency Department and Risk of Mortality in Children With Sepsis

Roni D. Lane,
Troy Richardson,
Halden F. Scott
et al.

Abstract: ImportancePediatric consensus guidelines recommend antibiotic administration within 1 hour for septic shock and within 3 hours for sepsis without shock. Limited studies exist identifying a specific time past which delays in antibiotic administration are associated with worse outcomes.ObjectiveTo determine a time point for antibiotic administration that is associated with increased risk of mortality among pediatric patients with sepsis.Design, Setting, and ParticipantsThis retrospective cohort study used data f… Show more

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