2023
DOI: 10.1101/2023.10.14.562338
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Deletion of SMC renders FtsK essential inCorynebacterium glutamicum

Feng Peng,
Giacomo Giacomelli,
Fabian Meyer
et al.

Abstract: Structural maintenance of chromosomes (SMC) are ubiquitously distributed proteins involved in chromosome organization. Deletion of smc causes severe growth phenotypes in many organisms. Surprisingly, smc can be deleted inCorynebacterium glutamicum, a member of the Actinomycetota phylum, without any apparent growth phenotype. Earlier work has shown that SMC inC. glutamicumis loaded in a ParB-dependent fashion to the chromosome and functions in replichore cohesion. The unexpected absence of a growth phenotype in… Show more

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