Delftia acidovorans bacteremia caused by bacterial translocation after organophosphorus poisoning in an immunocompetent adult patient

Hagiya, Hideharu; Murase, Tomoko; Sugiyama, Junichi; Kuroe, Yasutoshi; Nojima, Hiroyuki; Naito, Hiromichi; Hagioka, Shingo; Morimoto, Naoki

doi:10.1007/s10156-012-0472-x

Cited by 22 publications

(17 citation statements)

References 9 publications

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“…Epidemiology of D. acidovorans infections is not easy to elucidate. When determined, the source of infection can be river water (Reina et al, 1991), various devices and equipment in hospitals and clinics (Miño de Kaspar et al, 2000;Stampi et al, 1999;Stiegler et al, 2003;Weinstein et al, 1976), and paraphernalia contaminated with water used by intravenous drug abusers (Horowitz et al, 1990;Mahmood et al, 2012;Perla and Knutson, 2005), demonstrating the environmental origin of these bacteria (Steinberg and Burd, 2009). Bacteremia due to bacterial translocation from the bowel (Hagiya et al, 2013) or ascending urinary tract infection (Kam et al, 2012) or following a thoraco-abdominal gunshot wound (Oliver et al, 2005) has been reported as well as intravascular dispositive-related bloodstream infections (Castagnola et al, 1994;Chotikanatis et al, 2011;Kawamura et al, 2011;Lang et al, 2012).…”

Section: Introductionmentioning

confidence: 98%

Microbiological characterization of Delftia acidovorans clinical isolates from patients in an intensive care unit in Brazil

Camargo

Ferreira

Javaroni

et al. 2014

Diagnostic Microbiology and Infectious Disease

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Section: Introductionmentioning

confidence: 98%

Microbiological characterization of Delftia acidovorans clinical isolates from patients in an intensive care unit in Brazil

Camargo

Ferreira

Javaroni

et al. 2014

Diagnostic Microbiology and Infectious Disease

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“…Recently, Hagiya and colleagues reported a D. acidovorans bacteremia in a 46-year-old woman caused by translocation of the bacteria after pesticide poisoning (15). Bacteremia caused by C. testosteroni was previously reported in a 22-year-old man with a perforated appendix (21).…”

mentioning

confidence: 97%

“…Although they are ubiquitously distributed in the environment (soil and water), Comamonas and Delftia species are rarely associated with infections in humans. However, several publications have incriminated C. testosteroni and D. acidovorans in particular in human diseases, including severe invasive infections such as bacteremia and meningitis (7,(11)(12)(13)(14)(15)(16)(17).…”

mentioning

confidence: 99%

“…Like D. acidovorans, C. testosteroni is the Comamonas species associated predominantly with bacteremia (Table 1) (7,14,15,17,21). Translocation from the digestive tract and catheters is the predominant source of infection (15,17,21,23).…”

mentioning

confidence: 99%

“…Translocation from the digestive tract and catheters is the predominant source of infection (15,17,21,23). Immunocompromised children or patients with compromised immune systems such as patients with AIDS or patients with cancer or treated with aplastic chemotherapies appear to be particularly at risk of developing Comamonas sp.…”

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confidence: 99%

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Bacteremia Caused by Comamonaskerstersii in a Patient with Diverticulosis

et al. 2014

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We report for the first time a case of bacteremia caused by Comamonas kerstersii in a 65-year-old patient with sign of diverticulosis. In addition, we review the isolation of Comamonas sp. and related organisms in our hospital over 25 years. CASE REPORTC omamonas kerstersii is a nonfermenting betaproteobacterium described in 2003 that has long been considered nonpathogenic (1). This organism has recently been associated with intraabdominal infection due to perforation of the digestive tract (2). Here we describe a case of polymicrobial bacteremia due to C. kerstersii and Bacteroides fragilis in a 65-year-old diabetic man who was admitted to the emergency department of a hospital because of the sudden onset of fever and chills. The patient reported episodes of vomiting and diarrhea and mentioned that he had drunk water from a small river. Stool cultures performed after the beginning of antibiotic treatment did not disclose Salmonella, Shigella, Aeromonas, Campylobacter species, or C. kerstersii. The detection of Clostridium difficile toxins A and B and glutamate dehydrogenase antigen with the commercial C. difficile detection kit from Techlab was also negative. Blood samples (two pairs of culture bottles) were drawn from a peripheral vein, and the patient was discharged under treatment with oral ciprofloxacin for gastroenteritis of unknown origin. The blood cultures were processed by a Bactec FX automated blood culture system (Becton, Dickinson, Sparks, MD). A first aerobic blood culture bottle became positive 16 h 8 min after sampling, and Gram staining revealed the presence of long, filamentous, Gram-negative bacilli (Fig. 1). Bacterial identification by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (Bruker Daltonics GmbH, Leipzig, Germany) was performed on the same day by using a protocol that we recently developed on the basis of the analyses of a bacterial pellet preparation from the blood culture bottles (3-5). The strain was identified as C. kerstersii, a Gram-negative nonfermenting bacterium, and prompted the hospitalization of the patient. The patient was afebrile at that time, but palpation of the left lower abdominal quadrant was painful. An abdominal computed tomography (CT) scan revealed diverticulosis without evidence of diverticulitis. The anaerobic blood culture bottles from the same pair of samples became positive for Bacteroides fragilis 24 h 2 min after sample collection. We determined the following MICs (mg/liter) for the C. kerstersii strain by the Etest method

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Effect of heat stress on ileal microbial community of indigenous yellow‐feather broilers based on 16S rRNA gene sequencing

Jin

Guo

Zheng

et al. 2022

Veterinary Medicine & Sci

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Objectives:The broiler chickens are susceptible to heat stress (HS), including the indigenous broilers raised in tropical and subtropical regions. HS caused intestinal dysfunction and disrupted the gut microbiota. However, the researches about the effects of HS on ileal microbiome of indigenous broilers are limited. Therefore, this experiment used 16S rRNA sequencing to analyse the ileal microbial community in indigenous yellow-feather broilers under HS. Material and methods:The single factor completely random design was used in the present study, and forty 8-week-old Chinese indigenous yellow-feather broilers (Huaixiang chickens) were randomly divided into two treatments: normal temperature (NT) group and HS group. There are five replications with four broilers per replicate in each group. The broilers in NT group were raised at 21.3 ± 1.2 • C during the whole experimental period, the broilers in HS group were exposed to 32.5 ± 1.4 • C for 8 h/day from 9:00 am to 17:00 pm and the temperature of rest time is consistent with NT group.The experiment lasted for 4 weeks. Results:The results showed that HS exposure had no significant effects on the alpha diversity index of ileal microflora of broilers, including the Shannon, Simpson, Chao1 and ACE indexes (p > 0.05). At the genus level, HS significantly reduced the relative abundance of Campylobacter (p < 0.05), and increased the abundance of Delftia (p < 0.05). In addition, prediction of microbial community function indicated that HS significantly enhanced the abundance of the microflora related to lipid metabolism, carbohydrate metabolism and xenobiotics biodegradation and metabolism and reduced the abundance of the microflora related to nucleotide metabolism and amino acid metabolism. Conclusions:Taken together, the present study revealed that chronic HS (4 weeks) exposure changes the abundance of the ileal microflora of broilers. These findingsThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Delftia acidovorans bacteremia caused by bacterial translocation after organophosphorus poisoning in an immunocompetent adult patient

Cited by 22 publications

References 9 publications

Microbiological characterization of Delftia acidovorans clinical isolates from patients in an intensive care unit in Brazil

Microbiological characterization of Delftia acidovorans clinical isolates from patients in an intensive care unit in Brazil

Bacteremia Caused by Comamonaskerstersii in a Patient with Diverticulosis

Effect of heat stress on ileal microbial community of indigenous yellow‐feather broilers based on 16S rRNA gene sequencing

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