Delirium incidence, predictors and outcomes in the intensive care unit: A prospective cohort study

Abstract

AimThe aim of this study was to investigate the incidence, predictors, and outcomes of delirium in intensive care units.BackgroundDelirium is a common complication in intensive care units. In developing countries, it can be misdiagnosed or unrecognised.DesignProspective cohort study reported according to the strengthening the reporting of observational studies in epidemiology criteria.MethodsWe included patients who were conscious, >18 years old, and admitted to the intensive care units for at least 8 h between December 2019 and February 2020. Patients with a Richmond score of −4 or −5, mental disability, receptive aphasia and/or visual or auditory impairment were excluded from the study. Delirium was assessed using the Confusion Assessment Method for the ICU (CAM‐ICU), whereas the functional outcome was assessed by the Katz Activity of Daily Living Index.ResultsThis study included 111 patients with a delirium incidence of 31.5%. The severity of illness was the only significant predictor of delirium. Patients with delirium had longer intensive care unit and in‐hospital stays in contrast to those without delirium. Delirium was associated with in‐hospital and 4‐month mortality but not the activities of daily living.ConclusionsDelirium is associated with increased length of stay and mortality. Further investigation to determine whether delirium management can improve outcomes is warranted.

Discovery of Delirium Biomarkers through Minimally Invasive Serum Molecular Fingerprinting

“…In this cohort, the prevalence of delirium was significantly higher among males (p = 0.029) and factors such as the use of IMV, a longer length of ICU stay and the administration of oxazepam and midazolam were associated with an increased risk of its development (p < 0.001). These findings align with other studies regarding the impact of gender and treatment on the occurrence and severity of delirium [3,6,10,34,52].…”