Delirium is a Strong Predictor of Mortality in Patients Receiving Non-invasive Positive Pressure Ventilation

Chan, Kit Ying; Cheng, Suet-Lai; Mak, Ivan Wing Chit; Ng, Shu-Wah; Yiu, Michael Gar Chung; Chu, Chung Ming

doi:10.1007/s00408-016-9955-3

Cited by 19 publications

(7 citation statements)

References 44 publications

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“…All reasons for exclusion are detailed in Figure 1. We included 18 studies [33][34][35][36][37][38][39][40][41][42][43][44][45][46][47], adding to 15 studies from the original review.…”

Section: Resultsmentioning

confidence: 99%

The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study

Gibb

Seeley

Quinn

et al. 2019

Preprint

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“…All reasons for exclusion are detailed in Figure 1. We included 18 studies [33][34][35][36][37][38][39][40][41][42][43][44][45][46][47], adding to 15 studies from the original review.…”

Section: Resultsmentioning

confidence: 99%

The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study

Gibb

Seeley

Quinn

et al. 2019

Preprint

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“…mask intolerance). These findings may explain why the 30-day survival is 95% in non-delirious group and 78% in the delirious group [32].…”

Section: High Intensity Scenariomentioning

confidence: 88%

Acute care hospital at different levels of intensity: the role of Geriatrician

et al. 2018

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The traditional model of care is based on "disease-centered" management that requires the organization of the hospital in specialized wards, to which the patient is assigned for the main disease. The growing need to optimize economical and human resources and to promote a global approach to the patient has led to the setting up of the intensity of care model. It is a health system based on a "patient-centered" approach, where the hospital is organized in departments dedicated to patients with homogenous needs of care. In Italy, intensity of care model is currently being tested in the hospital organization, where three levels of intensity are proposed: low, medium and high. The purpose of the following review is to describe the role and importance of the Geriatrician in each of these care settings and to highlight the contradiction of a National Health System which promotes the geriatric approach to all types of patients, but does not invest in the formation and integration of the figure of the Geriatrician in clinical practice, condemning it to marginalization or even extinction.

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“…Therefore, the report of this systematic review is inaccurate. Another study was published at 2016 [25]. It enrolled 153 hypercapnic patients, and only reported the association between delirium and 1-year mortality.…”

Section: Discussionmentioning

confidence: 99%

“…It enrolled 153 hypercapnic patients, and only reported the association between delirium and 1-year mortality. As the small sample size, no one reported the situation in different subtypes of delirium [21][22][23][24][25]. However, we enrolled 1083 NIV patients involving different age and diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Incidence, Characteristics and Outcomes of Delirium in Patients With Noninvasive Ventilation: A Prospective Observational Study

Zhang

Bai

Han

et al. 2020

Preprint

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Background: Knowledge of delirium in noninvasive ventilation (NIV) is lacking. We aimed to report the incidence, characteristics and outcomes of delirium in NIV patients. Methods: A prospective observational study was performed in an intensive care unit (ICU) of a teaching hospital. Patients who used NIV as a fist-line intervention were enrolled. During NIV intervention, delirium was screened using Confusion Assessment Method for the ICU every day. Results: We enrolled 1083 patients. Of them, 196 patients (18.1%) experienced delirium during NIV intervention. Patients with delirium had higher NIV failure rates (37.8% vs. 21.0%, p ＜0.01), higher ICU mortality (33.2% vs. 14.3%, p ＜0.01) and higher hospital mortality (37.2% vs. 17.0%, p ＜0.01) than the subjects without delirium. They also spent longer time on NIV (median 6.3 vs. 3.7 days, p ＜0.01), and stayed longer in ICU (median 9.0 vs. 6.0 days, p ＜0.01) and hospital (median 14.5 vs. 11.0 days, p ＜0.01). Furthermore, delirium was independently associated with NIV failure, ICU mortality and hospital mortality (OR =1.97, 2.58 and 2.55, respectively; all p values ＜0.01). These results were confirmed in COPD and non-COPD cohorts. Compared with hyperactive delirium patients, the NIV days was longer in hypoactive delirium patients and much longer in mixed delirium patients (median 3.4 vs. 6.5 vs. 10.1 days, p ＜0.01). Similar outcomes were found in the length of stay in ICU and hospital. However, the NIV failure, ICU mortality and hospital mortality did not differ between three subtypes of delirium.Conclusions: Delirium increases the NIV failure rates, elevates the ICU and hospital mortality, prolongs the NIV days, and lengthens the ICU and hospital stay. Mixed delirium patients use more ICU resources than hypoactive delirium patients and much more than hyperactive delirium patients.

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Delirium is a Strong Predictor of Mortality in Patients Receiving Non-invasive Positive Pressure Ventilation

Cited by 19 publications

References 44 publications

The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study

The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study

Acute care hospital at different levels of intensity: the role of Geriatrician

Incidence, Characteristics and Outcomes of Delirium in Patients With Noninvasive Ventilation: A Prospective Observational Study

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