Delivery in pregnant women infected with <scp>SARS</scp>‐CoV‐2: A fast review

Parazzini, Fabio; Bortolus, Renata; Mauri, Paola Agnese; Favilli, Alessandro; Gerli, Sandro; Ferrazzi, E.

doi:10.1002/ijgo.13166

Cited by 88 publications

(94 citation statements)

References 24 publications

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“…Pathogen‐specific IgG can pass through the placenta as early as 12 weeks of gestation and exist in neonates for several months. In three neonates delivered by COVID‐19 mother, SARS‐CoV‐2 IgG levels were elevated and the RT‐PCR test was negative noting that antibody transmission through placental 39 . Convalescent plasma as a potential therapy for COVID‐19 suggesting the maternal antibodies may provide protective effects on newborns.…”

Section: The Immune Response In Pregnant Women Infected With Sars‐covmentioning

confidence: 99%

Potential effects of SARS‐CoV‐2 infection during pregnancy on fetuses and newborns are worthy of attention

Dang

Wang

Zhang

et al. 2020

J of Obstet and Gynaecol

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The outbreak of the 2019 novel coronavirus disease (SARS-CoV-2) has resulted in a major epidemic threat worldwide. However, the effects of neoviruses on infected pregnant women and especially on their fetuses and newborns are not well understood. Most up-to-date evidences about how SARS-CoV-2 affected patients especially in pregnancy were collected by conducting a comprehensive search of medical literature electronic databases. Immune-related data of pregnant women, fetuses and newborns were further analysis. According to the limited literature, SARS-CoV-2 utilizes angiotensin converting enzyme 2 as its receptor and causes severe hypoxemia. Insufficiency of angiotensin converting enzyme 2 in pregnant women and the effects of hypoxia on the placental oxygen supply will cause severe perinatal complications. In addition, SARS-CoV-2 infection may disrupt maternal-fetal immune tolerance and cause immunological damage to embryos. Because of these reasons, pregnancy complications such as fetal demise or premature birth, preeclampsia, intrauterine growth restriction, respiratory dyspnea, nervous system dysplasia and immune system defects are likely to occur in pregnant women with COVID-19 or their newborns. Pregnant women infected with SARS-CoV-2 should be treated as a special group and given special attention. Fetuses and newborns of SARS-CoV-2-infected pregnant women should be given more protection to reduce the occurrence of adverse events. In this review, we intend to provide an overview of the physiological and immunological changes that induce the pregnancy complications. This article will benefit the treatment and prognosis of fetuses and newborns of SARS-CoV-2-infected pregnant women.

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Section: The Immune Response In Pregnant Women Infected With Sars‐covmentioning

confidence: 99%

Potential effects of SARS‐CoV‐2 infection during pregnancy on fetuses and newborns are worthy of attention

Dang

Wang

Zhang

et al. 2020

J of Obstet and Gynaecol

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“…Special attention should be paid to pregnant women whose general condition is proved to be worse than others (4). Thus, caesarean section for infected or suspected pregnant women is the most challenging emergency surgery.…”

Section: Emergency Surgerymentioning

confidence: 99%

Suggestions on surgical treatment during coronavirus disease 2019 (COVID-19) pandemic

Zhao

Liu

2020

BST

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“…Однако IgM мог продуцировать сам младенец, если вирус, вызывающий COVID-19, проник в плаценту. Наши данные совпадают с результатами китайских исследователей, полученными на меньшем числе наблюдений [8][9][10]…”

Section: обсуждение результатовunclassified

Антитела IgM и IgG к вирусу SARS-Cov-2 у новорожденных от матерей с COVID-19

Semeshkin¹,

Вечорко²,

Силаев³

et al. 2020

Вестник РГМУ

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Исследование иммунитета у новорожденных, родившихся от матерей с доказанной новой коронавирусной инфекцией COVD-19, — малоизученный в настоящее время вопрос. Целью работы было проанализировать уровень иммуноглобулинов IgM и IgG к вирусу SARS-CoV-2. Исследование проводили у 20 матерей в возрасте 19–39 лет и 21 новорожденного (родилась одна двойня). В случае обнаружения повышенного уровня иммуноглобулинов IgM, IgG к вирусу SARS-CoV-2 у матери у новорожденного выявляли повышенный уровень IgG. Имеется предположение, что иммуноглобулины IgM к вирусу SARS-CoV-2 не проникают через плаценту от матери к ребенку. Во всех наблюдениях исследование с помощью ПЦР у новорожденных показало отрицательный результат, таким образом, вертикального пути передачи COVID-19, по всей видимости, нет. Необходимы дальнейшие исследования.

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Delivery in pregnant women infected with SARS‐CoV‐2: A fast review

Cited by 88 publications

References 24 publications

Potential effects of SARS‐CoV‐2 infection during pregnancy on fetuses and newborns are worthy of attention

Potential effects of SARS‐CoV‐2 infection during pregnancy on fetuses and newborns are worthy of attention

Suggestions on surgical treatment during coronavirus disease 2019 (COVID-19) pandemic

Антитела IgM и IgG к вирусу SARS-Cov-2 у новорожденных от матерей с COVID-19

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