Delivery systems in nanocosmeceuticals

Martel-Estrada, Santos-Adriana; Morales-Cardona, Andrea-Isabel; Vargas-Requena, Claudia; Rubio-Lara, Juan-Antonio; Martínez-Pérez, Carlos-Alberto; Jiménez-Vega, Florinda

doi:10.1515/rams-2022-0282

Cited by 11 publications

(4 citation statements)

References 209 publications

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“…Nanoparticles can be used to deliver sun-blocking agents, improving the stability and distribution of sunscreens on the skin. [434][435][436][437][438][439][440] In agriculture, nanoparticles and microencapsulation are utilized for the controlled release of fertilizers, pesticides, and growth regulators. This promotes precision farming, reduces environmental impact, and enhances crop yield.…”

Section: Application -Therapy Diagnostic Imaging Cosmetics Nutraceuti...mentioning

confidence: 99%

Nanoscale materials at work: Mapping emerging applications in energy, medicine, and beyond

Hughes,

Ganesan,

Tenchov

et al. 2024

Preprint

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Since their inception in the early 1960s, the use of nanoscale materials has progressed in leaps and bounds, and their role in diverse fields ranging from human health to energy is undeniable. In this report, we utilize the CAS Content Collection, a vast repository of scientific information extracted from journal and patent publications, to identify emerging topics in this field. This involves understanding trends, such as the growth of certain topics over time, as well as establishing relationships between emerging topics. We achieved this by using a host of strategies including a quantitative natural language processing (NLP) approach to identify 279 emerging topics and sub-topics across three major categories – materials, applications, and properties – by surveying roughly 3 million publications in the nanoscience landscape. This wealth of information has been condensed into several conceptual mind maps and other graphs that provide metrics related to the growth of identified emerging concepts, group them into hierarchical classes, and explore the connections between them. We delved deeper into four major emerging applications of nanoscale materials – drug delivery, sensors, energy, and catalysis – to provide a more comprehensive and detailed picture of the use of nanotechnology in these fields. In addition, we leveraged the CAS registry, consisting of over 250 million substances, to determine and discover substances across varied classes (such as polymers, elements, organic/inorganic molecules) and how they are utilized in the 4 major applications. Our extensive analysis taking advantage of an NLP-based approach along with robust CAS indexing provides valuable insights in the field that we hope can help to inform and drive future research efforts.

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Section: Application -Therapy Diagnostic Imaging Cosmetics Nutraceuti...mentioning

confidence: 99%

Nanoscale materials at work: Mapping emerging applications in energy, medicine, and beyond

Hughes,

Ganesan,

Tenchov

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Compared with conventional monolayer emulsion, bilayer or multilayer emulsions prepared using this technology have greater stability and longer shelf lives due to the thick and dense interfacial layers, high electrostatic repulsion, and good interfacial properties. The formation of thick interfacial layers around oil droplets by electrostatic layer self-assembly can be used as a strategy to protect lipolytic functional factors from degradation and improve their bioaccessibility [16].…”

Section: Introductionmentioning

confidence: 99%

Enhancing the Stability and Bioaccessibility of Tree Peony Seed Oil Using Layer-by-Layer Self-Assembling Bilayer Emulsions

Wang

et al. 2023

Antioxidants

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Tree peony seed oil (TPSO) is an important plant source of n-3 polyunsaturated fatty acid (α-linolenic acid, ALA > 40%) that is receiving increasing attention for its excellent antioxidant and other activities. However, it has poor stability and bioavailability. In this study, a bilayer emulsion of TPSO was successfully prepared using a layer-by-layer self-assembly technique. Among the proteins and polysaccharides examined, whey protein isolate (WPI) and sodium alginate (SA) were found to be the most suitable wall materials. The prepared bilayer emulsion contained 5% TPSO, 0.45% whey protein isolate (WPI) and 0.5% sodium alginate (SA) under selected conditions and its zeta potential, droplet size, and polydispersity index were −31 mV, 1291 nm, and 27%, respectively. The loading capacity and encapsulation efficiency for TPSO were up to 84% and 90.2%, respectively. It was noteworthy that the bilayer emulsion showed significantly enhanced oxidative stability (peroxide value, thiobarbituric acid reactive substances content) compared to the monolayer emulsion, which was accompanied by a more ordered spatial structure caused by the electrostatic interaction of the WPI with the SA. This bilayer emulsion also exhibited markedly improved environmental stability (pH, metal ion), rheological properties, and physical stability during storage. Furthermore, the bilayer emulsion was more easily digested and absorbed, and had higher fatty acid release rate and ALA bioaccessibility than TPSO alone and the physical mixtures. These results suggest that bilayer emulsion containing WPI and SA is an effective TPSO encapsulation system and has significant potential for future functional food development.

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“…For drug delivery, Pickering emulsions can provide controlled release of drugs and improve their bioavailability [38,39]. In the food industry, they can be used to encapsulate flavorings or nutrients, and in cosmetics, they can be used to stabilize emulsions and enhance the skin-penetrating ability of active ingredients [40][41][42]. In this study, bioactive compound-loaded ZnAC (MA-OHE/ZnAC) was encapsulated using a Pickering emulsion system, and its antimicrobial efficacy was evaluated.…”

Section: Introductionmentioning

confidence: 99%

A Bioactive Compound-Loaded Zinc-Aminoclay Encapsulated, Pickering Emulsion System for Treating Acne-Inducing Microbes

Kim

Bae²,

Lee

et al. 2023

IJMS

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Acne is a common skin condition caused by the growth of certain bacteria. Many plant extracts have been investigated for their potential to combat acne-inducing microbes, and one such plant extract is microwave-assisted Opuntia humifusa extract (MA-OHE). The MA-OHE was loaded onto zinc-aminoclay (ZnAC) and encapsulated in a Pickering emulsion system (MA-OHE/ZnAC PE) to evaluate its therapeutic potential against acne-inducing microbes. Dynamic light scattering and scanning electron microscopy were used to characterize MA-OHE/ZnAC PE with a mean particle diameter of 353.97 nm and a PDI of 0.629. The antimicrobial effect of MA-OHE/ZnAC was evaluated against Staphylococcus aureus (S. aureus) and Cutibacterium acnes (C. acnes), which contribute to acne inflammation. The antibacterial activity of MA-OHE/ZnAC was 0.1 and 0.025 mg/mL to S. aureus and C. acnes, respectively, which were close to naturally derived antibiotics. Additionally, the cytotoxicity of MA-OHE, ZnAC, and MA-OHE/ZnAC was tested, and the results showed that they had no cytotoxic effects on cultured human keratinocytes in a range of 10–100 μg/mL. Thus, MA-OHE/ZnAC is suggested to be a promising antimicrobial agent for treating acne-inducing microbes, while MA-OHE/ZnAC PE is a potentially advantageous dermal delivery system.

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Delivery systems in nanocosmeceuticals

Cited by 11 publications

References 209 publications

Nanoscale materials at work: Mapping emerging applications in energy, medicine, and beyond

Nanoscale materials at work: Mapping emerging applications in energy, medicine, and beyond

Enhancing the Stability and Bioaccessibility of Tree Peony Seed Oil Using Layer-by-Layer Self-Assembling Bilayer Emulsions

A Bioactive Compound-Loaded Zinc-Aminoclay Encapsulated, Pickering Emulsion System for Treating Acne-Inducing Microbes

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