Delusional disorder: an overview of affective symptoms and antidepressant use

González-Rodríguez, Alexandre; Molina-Andreu, Oriol; Odriozola, Víctor Navarro; Ferrer, Cristobal Gastó; Penadés, Rafael; Catalán, Rosa

doi:10.4321/s0213-61632013000400005

Cited by 16 publications

(7 citation statements)

References 36 publications

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“…There is evidence of delusional disorders occurring comorbidly with depressive disorder and that this may occur particularly frequently for the somatic subtype 7 8. Depressive disorders with somatic delusions do not seem distinct from depression with other types of psychotic symptoms 9.…”

Section: Discussionmentioning

confidence: 99%

Treatment resistant somatic delusions in bipolar disorder

Slattery

Nance

2015

BMJ Case Reports

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SUMMARYTwo patients each developed a single, fixed somatic delusion complicating their existing bipolar disorder. Both failed to respond to a range of antidepressant and antipsychotic medications. They each showed a partial response to clozapine and to electroconvulsive therapy, with resolution of mood symptoms and diminution of their ongoing somatic preoccupation. A review of case reports suggests a possible relationship between somatic delusions and affective disorders. BACKGROUND

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Section: Discussionmentioning

confidence: 99%

Treatment resistant somatic delusions in bipolar disorder

Slattery

Nance

2015

BMJ Case Reports

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“…The study concluded that major depression and schizophrenia commonly co-existed but that schizophrenia eclipsed the depression, which was left untreated, thus negatively affecting the outcome of illness. A recent systematic review and meta-analysis [22] confirmed the frequency of this co-morbidity, recommending that antidepressants be more frequently used in schizophrenia [22], a currently uncommon practice [23].…”

Section: The Association Between Pain and Psychotropic Medications Inmentioning

confidence: 99%

Pain Sensitivity in Schizophrenia Spectrum Disorders: A Narrative Review of Recent Work

González-Rodríguez

Labad

Seeman

2021

Psychiatry International

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Many patients with schizophrenia seem relatively immune to physical pain while others complain of constant pain. This may result from disturbances or alterations of the sensory threshold for pain in populations with psychosis, a possibility for which there is some preliminary evidence. The inconsistency in pain perception may, in part, be explained by the treatments patients receive, but treatment-naïve patients also exhibit differences in response to pain. This suggests that decreased pain sensitivity may represent a specific psychosis endophenotype. Thus far, few experimental studies have investigated sensory thresholds, pain modalities, or other factors contributing to the perception or expression of physical pain in psychosis. A digital search for information on this topic was conducted in PubMed and Google Scholar. The result is a non-systematic, narrative review focusing on recent clinical and experimental findings of pain sensitivity in patients with psychosis. Importantly, physical and mental pain are closely connected constructs that may be difficult to differentiate. Our hope is that the review provides some clarity to the field in the specific context of schizophrenia.

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“…Patients with DD frequently suffer from comorbidities, mainly mood disorders and especially depressive disorders. Although exact rates are not available, the prevalence of comorbid mood disorder is estimated to be between 21% and 58% [6].…”

Section: Gender Differences In Psychiatric Co-morbiditymentioning

confidence: 99%

“…Accordingly, DSM-5 categorizes seven subtypes [1]. Comorbid conditions have also been identified, depression being the most common [5,6].…”

Section: Introductionmentioning

confidence: 99%

What We Know and Still Need to Know about Gender Aspects of Delusional Disorder: A Narrative Review of Recent Work

2019

J Psychiatry Brain Sci

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While gender differences in the psychopathology and clinical course of schizophrenia have been extensively reported, the potential for analogous differences in delusional disorder has been understudied. Our aim in this paper is to focus on the recent literature on delusional disorder and to explore gender aspects. This is a non-systematic, narrative and critical review. The review is divided into the following main sections: gender differences in epidemiology, symptomatology, phenotypic factor analyses, psychiatric comorbidity, response and adherence to medications, and clinical trajectories. Culture-bound delusional syndromes are also addressed, and potential causes for gender differences and their treatment are critically discussed. Although DMS-5 reports no gender differences in the frequency of delusional disorder or in delusional content, several studies have found erotomania to be more frequent in women. There seem also to be gender differences in affective and substance abuse comorbidity, which may prove clinically important. The loss of the neuroprotection conferred by estrogens during the reproductive period in women may trigger depressive symptoms after menopause. The interaction of age and gender has been insufficiently studied as is also the case for selective cultural pressures on men and women and their impact on the content of delusions. Studies designed to focus on gender differences in response to treatment are currently needed in delusional disorder.

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Delusional disorder: an overview of affective symptoms and antidepressant use

Cited by 16 publications

References 36 publications

Treatment resistant somatic delusions in bipolar disorder

Treatment resistant somatic delusions in bipolar disorder

Pain Sensitivity in Schizophrenia Spectrum Disorders: A Narrative Review of Recent Work

What We Know and Still Need to Know about Gender Aspects of Delusional Disorder: A Narrative Review of Recent Work

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