Delusional Infestation Can Be a Complication of Prurigo Nodularis with Underlying Neuropathies

Dervout, Charles; Stephan, F.; Miséry, Laurent

doi:10.2340/00015555-3579

Cited by 4 publications

(2 citation statements)

References 15 publications

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“…Interestingly, patients did not report higher impulsiveness or more traumatic life experiences than patients with chronic pruritus without skin lesions 60 . Some cases of delusional infestation as a complication of prurigo nodularis have been reported 61 …”

Section: Burdenmentioning

confidence: 89%

“…60 Some cases of delusional infestation as a complication of prurigo nodularis have been reported. 61 Using the Health Utilities Index Mark 3 questionnaire, a US study compared adults with chronic prurigo and controls and found worse health performance, which was most prominent in the pain subdomain, and an average of 6Á5 lifetime qualityadjusted life years lost per patient, translating to an individual lifetime economic burden of $323 292 and a societal burden of $38Á8 billion. 62…”

Section: Burdenmentioning

confidence: 99%

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Chronic prurigo

Miséry

2022

British Journal of Dermatology

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Chronic prurigo is a distinct disease defined by the presence of chronic pruritus for at least 6 weeks, a history and/or signs of repeated scratching, and multiple localized or generalized pruritic skin lesions (whitish or pinkish papules, nodules and/or plaques). Although chronic prurigo is frequently named prurigo nodularis, the nodular type of chronic prurigo is only the main clinical aspect of chronic prurigo. Chronic prurigo occurs due to neural sensitization to pruritus and the development of a vicious pruritus-scratching cycle. Chronic prurigo can be of allergological, dermatological, systemic, neurological, psychiatric/psychosomatic, mixed or undetermined origin. The prevalence is still debated. The burden is high. Current treatments often remained disappointing. Fortunately, recent research results on the pathophysiology of pruritus evidenced neuroimmune interactions and allow new therapeutic perspectives. Among them, antagonists of T-helper 2 cytokines, j-opioids and Janus kinase inhibitors may be promising.a Definition of pruriginous lesion: excoriated, scaling and/or crusted papules and/or nodules and/or plaques, often with a whitish or pink centre and hyperpigmented border.

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Section: Burdenmentioning

confidence: 89%